Evidence map›Paper›PMID 34497078›Full record

Trial reportBMJ open2021

Effectiveness and safety of the adjunctive use of an internet-based self-management intervention for borderline personality disorder in addition to care as usual: results from a randomised controlled trial.

Jan Philipp Klein, Andrea Hauer-von Mauschwitz, Thomas Berger, Eva Fassbinder, Johannes Mayer, Stefan Borgwardt, Bernhard Wellhöfer, Ulrich Schweiger, Gitta Jacob

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03418142 (Research Evaluating the EffectiVeness of Adding an Internet-Based Self-Management Intervention to Usual Care in the Treatment of Borderline Personality Disorder - REVISIT BPD), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03418142 nacompletednot on this map

Research Evaluating the EffectiVeness of Adding an Internet-Based Self-Management Intervention to Usual Care in the Treatment of Borderline Personality Disorder - REVISIT BPD

TypeinterventionalSponsorGaia AGRan2018 to 2020Enrolled206ConditionsBorderline Personality DisorderArmsPriovi, CAU
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jan Philipp Klein *Department of Psychiatry, Psychosomatics and Psychotherapy, University of Lübeck, Lubeck, Germany philipp.klein@uksh.de.ORCID 0000-0001-9882-2261
Andrea Hauer-von Mauschwitz *Gaia AG, Hamburg, Germany.
Thomas BergerDepartment of Clinical Psychology and Psychotherapy, University of Bern, Bern, Switzerland.ORCID 0000-0002-2432-7791
Eva FassbinderDepartment of Psychiatry, Psychosomatics and Psychotherapy, University of Lübeck, Lubeck, Germany.
Johannes MayerGaia AG, Hamburg, Germany.
Stefan BorgwardtDepartment of Psychiatry, Psychosomatics and Psychotherapy, University of Lübeck, Lubeck, Germany.ORCID 0000-0002-5792-3987
Bernhard WellhöferGaia AG, Hamburg, Germany.
Ulrich SchweigerDepartment of Psychiatry, Psychosomatics and Psychotherapy, University of Lübeck, Lubeck, Germany.
Gitta JacobGaia AG, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceBorderline personality disorder (BPD) is a severe mental disorder that is often inadequately treated.

objectiveTo determine if adding a self-management intervention to care as usual (CAU) is effective and safe.

designRandomised, controlled, rater-blind trial. Duration of treatment and assessments: 12 months.

settingSecondary care, recruited mainly via the internet.

participantsPatients with BPD and BPD Severity Index (BPDSI) of at least 15.

interventionsCAU by treating psychiatrist and/or psychotherapist alone or adjunctive use of an internet-based self-management intervention that is based on schema therapy (priovi).

main outcome measureOutcomes were assessed by trained raters. The primary outcome was change in BPDSI. The safety outcome was the number of serious adverse events (SAEs). The primary outcome time point was 12 months after randomisation.

resultsOf 383 participants assessed for eligibility, 204 were included (91.7% female, mean age: 32.4 years; 74% were in psychotherapy and 26% were in psychiatric treatment). The slope of BPDSI change did not differ significantly between groups from baseline to 12 months (F

conclusionsWe have not found a significant effect in favour of the intervention. This might be due to the unexpectedly large effect in the group receiving CAU by a psychiatrist and/or psychotherapist alone.

trial registrationNCT03418142.

Indexed as

Borderline Personality DisorderSelf-ManagementAdultCost-Benefit AnalysisFemaleHumansInternetMalePsychotherapyTreatment Outcomeadult psychiatryclinical trialspersonality disorderssuicide & self-harm

Identifiers

PMID34497078
PMCPMC8438831

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.