Evidence map›Paper›PMID 34499338›Full record

SynthesisSports medicine (Auckland, N.Z.)2021

The Effect of Resistance Training on Body Composition During and After Cancer Treatment: A Systematic Review and Meta-Analysis.

Briana Clifford, Sean Koizumi, Michael A Wewege, Hayley B Leake, Lauren Ha, Eliza Macdonald, Ciaran M Fairman, Amanda D Hagstrom

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  4. Does Androgen Deprivation for Prostate Cancer Affect Normal Adaptation to Resistance Exercise?International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Briana CliffordDepartment of Exercise Physiology, School of Health Sciences, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0003-4392-795X
Sean KoizumiDepartment of Exercise Physiology, School of Health Sciences, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0003-0572-5943
Michael A WewegeDepartment of Exercise Physiology, School of Health Sciences, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0002-3283-2149
Hayley B LeakeCentre for Pain IMPACT, Neuroscience Research Australia, Sydney, NSW, Australia.ORCID 0000-0002-6133-2186
Lauren HaDepartment of Exercise Physiology, School of Health Sciences, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0001-6494-5861
Eliza MacdonaldDepartment of Exercise Physiology, School of Health Sciences, University of New South Wales, Sydney, NSW, Australia.ORCID 0000-0001-5372-8378
Ciaran M FairmanExercise Science Department, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.ORCID 0000-0001-8834-9669
Amanda D HagstromDepartment of Exercise Physiology, School of Health Sciences, University of New South Wales, Sydney, NSW, Australia. m.hagstrom@unsw.edu.au.ORCID 0000-0002-8036-9216
The University of Sydney · AUUniversity of South Australia · AUUniversity of South Carolina · USUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanges in body composition during cancer treatments have been linked with poorer outcomes, and increased morbidity and mortality. The effect of resistance training (RT) on body composition in cancer cohorts is debated.

objectiveWe conducted a systematic review and meta-analysis to determine the effect of RT on body composition during and after treatment.

methodsWe searched five electronic databases for articles up to 1 February 2021 and included randomized controlled trials that compared RT with a non-exercise control in adults with cancer. Risk of bias was assessed using the RoB 2 tool. Pairwise, random-effects meta-analysis was used to synthesize the available data.

resultsOverall, we included 15 studies (n = 1368). After treatment (11 studies), RT increased lean mass with moderate heterogeneity {0.41 kg [95% confidence interval (CI) 0.05, 0.76], p = 0.029; I

conclusionModest improvements in body composition were observed following RT after cancer treatment; however, no changes were observed during treatment. These adaptations are markedly lower than those observed in healthy cohorts but may be clinically meaningful for the cancer survivorship population. At present it is unclear if these diminished adaptations are due to ineffective exercise prescriptions in cancer cohorts or due to an innate anabolic resistance as a result of cancer and its treatments. STUDY REGISTRATION: Open Science Framework (osf.io/x6z72).

Indexed as

NeoplasmsResistance TrainingAdultBody CompositionExercise TherapyHealth StatusHumans

Identifiers

PMID34499338
OpenAlexW3197301508

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.