Evidence map›Paper›PMID 34500570›Full record

ArticleMolecules (Basel, Switzerland)2021

Concurrent Reactive Oxygen Species Generation and Aneuploidy Induction Contribute to Thymoquinone Anticancer Activity.

Mohammed Al-Hayali, Aimie Garces, Michael Stocks, Hilary Collins, Tracey D Bradshaw

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mohammed Al-HayaliAl-Mosul General Hospital, Mosul University Post Office, P.O. Box 11104, Mosul 41002, Iraq.
Aimie GarcesSchool of Pharmacy, Biodiscovery Institute, University Park, University of Nottingham, Nottingham NG7 2RD, UK.
Michael StocksSchool of Pharmacy, Biodiscovery Institute, University Park, University of Nottingham, Nottingham NG7 2RD, UK.
Hilary CollinsSchool of Pharmacy, Biodiscovery Institute, University Park, University of Nottingham, Nottingham NG7 2RD, UK.
Tracey D BradshawSchool of Pharmacy, Biodiscovery Institute, University Park, University of Nottingham, Nottingham NG7 2RD, UK.
University of Nottingham · GBUniversity of Mosul · IQ

Funding

Higher Committee for Education Development in Iraq D-10-2013
6 · The paper itself

Abstract

Thymoquinone (TQ) is the main biologically active constituent of

Indexed as

AneuploidyAntineoplastic AgentsApoptosisBenzoquinonesCell Line, TumorCell ProliferationHCT116 CellsHumansMCF-7 CellsNAD(P)H Dehydrogenase (Quinone)Nigella sativaReactive Oxygen SpeciesAntineoplastic AgentsBenzoquinonesNAD(P)H Dehydrogenase (Quinone)quinoneReactive Oxygen SpeciesthymoquinoneaneuploidyapoptosisGSH depletionROS generationthymoquinone

Identifiers

PMID34500570
PMCPMC8433634
OpenAlexW3195026739

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.