Evidence map›Paper›PMID 34501231›Full record

ArticleJournal of clinical medicine2021

Effects of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Non-Alcoholic Fatty Liver Disease: A 12-Month Follow-Up Study with Paired Liver Biopsies.

Julie Steen Pedersen, Marte Opseth Rygg, Reza Rafiolsadat Serizawa, Viggo Bjerregaard Kristiansen, Nicolai J Wewer Albrechtsen, Lise Lotte Gluud, Sten Madsbad, Flemming Bendtsen

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Foregut bypassHepatobiliary surgery and nutrition · 2023
    Article
  8. Review
  9. Review
  10. The Link between NAFLD and Metabolic Syndrome.Diagnostics (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Article
  13. Review
  14. Nonalcoholic fatty liver disease and diabetes.World journal of diabetes · 2022
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Julie Steen PedersenGastro Unit, Medical Division, Copenhagen University Hospital Hvidovre, Kettegaard Allé 30, 2650 Copenhagen, Denmark.
Marte Opseth RyggGastro Unit, Medical Division, Copenhagen University Hospital Hvidovre, Kettegaard Allé 30, 2650 Copenhagen, Denmark.
Reza Rafiolsadat SerizawaDepartment of Pathology, Copenhagen University Hospital Hvidovre, 2650 Copenhagen, Denmark.
Viggo Bjerregaard KristiansenGastro Unit, Surgical Division, Copenhagen University Hospital Hvidovre, 2650 Copenhagen, Denmark.
Nicolai J Wewer AlbrechtsenDepartment of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0003-4230-5753
Lise Lotte GluudGastro Unit, Medical Division, Copenhagen University Hospital Hvidovre, Kettegaard Allé 30, 2650 Copenhagen, Denmark.ORCID 0000-0002-9462-4468
Sten MadsbadDepartment of Endocrinology, Copenhagen University Hospital Hvidovre, 2650 Copenhagen, Denmark.
Flemming BendtsenGastro Unit, Medical Division, Copenhagen University Hospital Hvidovre, Kettegaard Allé 30, 2650 Copenhagen, Denmark.
Copenhagen University Hospital · DKUniversity of Copenhagen · DK

Funding

Aase og Ejnar Danielsens Fond 19-10-0284Michaelsen Fonden 10-100012Novo Nordisk Fonden 31526Novo Nordisk Fonden 34250Novo Nordisk Fonden NNF15OC0016692Novo Nordisk Fonden nnf19OC0055001
6 · The paper itself

Abstract

Roux-en-Y gastric bypass (RYGB) improves, and can sometimes resolve, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) but data based on histological assessment for the efficacy of sleeve gastrectomy (SG) in resolving NAFLD are sparse. Consequently, we aimed to compare the efficacy of RYGB vs. SG on NAFLD 12 months after surgery. In a prospective cohort study, 40 patients with obesity underwent bariatric surgery (16 RYGB and 24 SG). During surgery, a liver biopsy was taken and repeated 12 months later. NAFLD severity was evaluated using the NAFLD Activity Score (NAS) and Kleiner Fibrosis score. RYGB and SG patients were comparable at baseline. Mean (standard deviation, SD) NAS was 3.3 (0.9) in RYGB and 3.1 (1.4) in SG (

Indexed as

bariatric surgeryliver histologynon-alcoholic fatty liver diseasenon-alcoholic fatty liver disease activity scoreRoux-en-Y gastric bypasssleeve gastrectomy

Identifiers

PMID34501231
PMCPMC8432029
OpenAlexW3196275181

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.