Evidence map›Paper›PMID 34502178›Full record

ArticleInternational journal of molecular sciences2021

Identification and Validation of Esophageal Squamous Cell Carcinoma Targets for Fluorescence Molecular Endoscopy.

Xiaojuan Zhao, Qingfeng Huang, Marjory Koller, Matthijs D Linssen, Wouter T R Hooghiemstra, Steven J de Jongh, Marcel A T M van Vugt, Rudolf S N Fehrmann, Enmin Li, Wouter B Nagengast

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Novel milestones for early esophageal carcinoma: From bench to bed.World journal of gastrointestinal oncology · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Xiaojuan ZhaoDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Qingfeng HuangGuangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0003-1594-8884
Marjory KollerDepartment of Surgery, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-5205-118X
Matthijs D LinssenDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Wouter T R HooghiemstraDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-5349-0344
Steven J de JonghDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Marcel A T M van VugtDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Rudolf S N FehrmannDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
Enmin LiGuangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0001-6375-3614
Wouter B NagengastDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
University Medical Center Groningen · NLShantou University · CN

Funding

National Key R&D Program of China 2018YFC1313101
6 · The paper itself

Abstract

Dysplasia and intramucosal esophageal squamous cell carcinoma (ESCC) frequently go unnoticed with white-light endoscopy and, therefore, progress to invasive tumors. If suitable targets are available, fluorescence molecular endoscopy might be promising to improve early detection. Microarray expression data of patient-derived normal esophagus (

Indexed as

Gene Expression Regulation, NeoplasticEarly DiagnosisEndoscopyEsophageal Squamous Cell CarcinomaEsophagusFluorescenceGene Expression ProfilingGlucose Transporter Type 1HumansImmunohistochemistryNeoplasm ProteinsOligonucleotide Array Sequence AnalysisRNA, MessengerSensitivity and SpecificityGlucose Transporter Type 1Neoplasm ProteinsRNA, MessengerSLC2A1 protein, humanbioinformaticsearly detectionfluorescence molecular endoscopymRNA profilingsquamous high-grade dysplasia

Identifiers

PMID34502178
PMCPMC8431213
OpenAlexW3197985599

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.