Evidence map›Paper›PMID 34503169›Full record

ArticleCancers2021

Germline

Joana Figueiredo, Fátima Mercadillo, Soraia Melo, Alicia Barroso, Margarida Gonçalves, José Díaz-Tasende, Patrícia Carneiro, Luis Robles, Francisco Colina, Carolina Ibarrola and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Joana Figueiredoi3S-Instituto de Investigação e Inovação em Saúde, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-1590-1974
Fátima MercadilloFamilial Cancer Clinical Unit, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
Soraia Meloi3S-Instituto de Investigação e Inovação em Saúde, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0278-0827
Alicia BarrosoFamilial Cancer Clinical Unit, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
Margarida Gonçalvesi3S-Instituto de Investigação e Inovação em Saúde, University of Porto, 4200-135 Porto, Portugal.
José Díaz-TasendeEndoscopy Unit, Gastroenterology Department, 12 de Octubre Universitary Hospital, 28041 Madrid, Spain.
Patrícia Carneiroi3S-Instituto de Investigação e Inovação em Saúde, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-4404-9343
Luis RoblesFamilial Cancer Unit, Medical Oncology Service, 12 de Octubre Universitary Hospital, 28041 Madrid, Spain.
Francisco ColinaPathology Department, 12 de Octubre Universitary Hospital, 28041 Madrid, Spain.
Carolina IbarrolaPathology Department, 12 de Octubre Universitary Hospital, 28041 Madrid, Spain.
José PereaSurgery Department, Fundación Jiménez Díaz University Hospital, 28040 Madrid, Spain.ORCID 0000-0001-5522-8844
Eurico Morais-de-Sái3S-Instituto de Investigação e Inovação em Saúde, University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0003-3525-8231
Raquel Serucai3S-Instituto de Investigação e Inovação em Saúde, University of Porto, 4200-135 Porto, Portugal.
Miguel UriosteFamilial Cancer Clinical Unit, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.
Universidade do Porto · PTSpanish National Cancer Research Centre · ESHospital Universitario Fundación Jiménez Díaz · ES

Funding

Fundação para a Ciência e a Tecnologia CEECIND/00622/2017Fundação para a Ciência e a Tecnologia NORTE-01-0145-FEDER-000029Fundação para a Ciência e a Tecnologia PTDC/BIM-ONC/0281/2014Fundação para a Ciência e a Tecnologia PTDC/BTM-SAL/30383/2017Fundação para a Ciência e a Tecnologia PTDC/MED-GEN/30356/2017Fundação para a Ciência e a Tecnologia SFRH/BD/108009/2015-SMFundação para a Ciência e a Tecnologia SFRH/BD/130708/2017-MG
6 · The paper itself

Abstract

E-cadherin, encoded by

Indexed as

CDH1 missense variantE-cadherinfunctional assaysHDGC

Identifiers

PMID34503169
PMCPMC8430832
OpenAlexW3196511252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.