ArticleGenetics, selection, evolution : GSE2021
A genome-wide scan to identify signatures of selection in two Iranian indigenous chicken ecotypes.
Article in Genetics, selection, evolution : GSE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
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25 citing papers in PubMed, 54 citations in OpenAlex.
- Genomic signatures of environmental adaptation in Danzhou chickens.BMC genomics · 2026Article
- Population structure based on whole-genome resequencing and adaptive evolutionary mechanisms of circadian entrainment in the endangered fish Percocypris pingi.BMC genomics · 2026Article
- A review of genetic variation underlying chicken phenotypic diversity.Poultry science · 2025Review
- Whole genome sequencing and resequencing provide insight into the genetic structure of wild Ophiocordyceps sinensis.BMC genomics · 2025Article
- Search for Ancient Selection Traces in Faverolle Chicken Breed (Animals : an open access journal from MDPI · 2025Article
- Uncovering genomic diversity and signatures of selection in red Angus × Chinese red steppe crossbred cattle population.Scientific reports · 2025Article
- Population structure, selection signal and introgression of gamecocks revealed by whole genome sequencing.Journal of animal science and biotechnology · 2025Article
- Genomic scans for selection and runs of homozygosity in southern Italian turkey populations.Poultry science · 2025Article
- Comparative Analysis of Runs of Homozygosity Islands in Indigenous and Commercial Chickens Revealed Candidate Loci for Disease Resistance and Production Traits.Veterinary medicine and science · 2025Article
- Immunogenetic diversity of MHC class II B-Lβ genes in Brazilian Caipiras (free-range) chickens laying blue eggs.Frontiers in immunology · 2025Article
- Genome-Wide Scan for Selective Sweeps Reveals Novel Loci Associated with Prolificacy in Iranian Sheep Breeds in Comparison with Highly Prolific Exotic Breed.Animals : an open access journal from MDPI · 2024Article
- Danzhou chicken: a unique genetic resource revealed by genome-wide resequencing data.Poultry science · 2024Article
- Integrated transcriptomic analysis on chicken ovary reveals CYP21A1 affects follicle granulosa cell development and steroid hormone synthesis.Poultry science · 2024Article
- Article
- Genomic Inbreeding and Runs of Homozygosity Analysis of Cashmere Goat.Animals : an open access journal from MDPI · 2024Article
- Genotyping-by-Sequencing Strategy for Integrating Genomic Structure, Diversity and Performance of Various Japanese Quail (Animals : an open access journal from MDPI · 2023Article
- Article
- Identification of Runs of Homozygosity Islands and Functional Variants in Wenchang Chicken.Animals : an open access journal from MDPI · 2023Article
- Genome-wide mapping of signatures of selection using a high-density array identified candidate genes for growth traits and local adaptation in chickens.Genetics, selection, evolution : GSE · 2023Article
- Systematic Selection Signature Analysis of Chinese Gamecocks Based on Genomic and Transcriptomic Data.International journal of molecular sciences · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious regions of the chicken genome have been under natural and artificial selection for thousands of years. The substantial diversity that exits among chickens from different geographic regions provides an excellent opportunity to investigate the genomic regions under selection which, in turn, will increase our knowledge about the mechanisms that underlie chicken diversity and adaptation. Several statistics have been developed to detect genomic regions that are under selection. In this study, we applied approaches based on differences in allele or haplotype frequencies (F
resultsUsing whole-genome resequencing data of 32 individuals from the two chicken ecotypes, approximately 11.9 million single nucleotide polymorphisms (SNPs) were detected and used in genomic analyses after quality processing. Examination of the distribution of ROH in the two populations indicated short to long ROH, ranging from 0.3 to 5.4 Mb. We found 90 genes that were detected by at least two of the four applied methods. Gene annotation of the detected putative regions under selection revealed candidate genes associated with growth (DCN, MEOX2 and CACNB1), reproduction (ESR1 and CALCR), disease resistance (S1PR1, ALPK1 and MHC-B), behavior pattern (AGMO, GNAO1 and PSEN1), and morphological traits (IHH and NHEJ1).
conclusionsOur findings show that these two phenotypically different indigenous chicken populations have been under selection for reproduction, immune, behavioral, and morphology traits. The results illustrate that selection can play an important role in shaping signatures of differentiation across the genomic landscape of two chicken populations.
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