Evidence map›Paper›PMID 34505017›Full record

ArticleChronic diseases and translational medicine2021

Effects of methylenetetrahydrofolate reductase single-nucleotide polymorphisms on breast, cervical, ovarian, and endometrial cancer susceptibilities.

Zheng Wang, Kai Li, Ling Ouyang, Hidasa Iko, Ahmad Javid Safi, Shan Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chronic diseases and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Common Variants in One-Carbon Metabolism Genes (International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Zheng WangDepartment of Otorhinolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Kai LiDepartment of Surgical Oncology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Ling OuyangDepartment of Obstetrics and Gynecology, The Shengjing Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Hidasa IkoJapan Shouko Co. Ltd, Nisikujo 3-5-4 Konohanaku Osakashi Osakafu Japan, 554-0012, Japan.
Ahmad Javid SafiAfghanistan Cancer Foundation, Kart-e-Char, Kabul, Afghanistan.
Shan GaoDepartment of Obstetrics and Gynecology, The Shengjing Hospital of China Medical University, Shenyang, Liaoning 110001, China.
China Medical University · CNFirst Hospital of China Medical University · CNNihon Nohyaku (Japan) · JPWorld Health Organization - Afghanistan · AF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies identifying

methodsRelevant reports published before January 20, 2020, were retrieved from PubMed, Embase, the Cochrane Library, and the China National Knowledge Infrastructure databases. The odds ratio and 95% confidence interval summaries for the

resultsA total of 171 studies comprising 56,675 cancer cases and 67,559 controls were included. The results showed a markedly elevated risk of cancer susceptibility related to

conclusionThis meta-analysis suggests that

Indexed as

Breast cancerFemale genital neoplasmsMeta-analysisMethylenetetrahydrofolate reductasePolymorphism

Identifiers

PMID34505017
PMCPMC8413124
OpenAlexW3194573842

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.