Evidence map›Paper›PMID 34506262›Full record

ReviewBioengineered2021

CRISPR-Cas9-based genetic engineering for crop improvement under drought stress.

Abdul Sami, Zhao Xue, Saheera Tazein, Ayesha Arshad, Zong He Zhu, Ya Ping Chen, Yue Hong, Xiao Tian Zhu, Ke Jin Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 98 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Impact of Water Deficit Stress onPlants (Basel, Switzerland) · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. CRISPR-Based Editing of thePlants (Basel, Switzerland) · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Abdul SamiRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.ORCID 0000-0002-6098-5951
Zhao XueRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.
Saheera TazeinPgrl CABB, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Ayesha ArshadPlant Physiology Lab, Quaid I Azam University, Islamabad, Pakistan.
Zong He ZhuRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.
Ya Ping ChenRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.
Yue HongRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.
Xiao Tian ZhuRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.
Ke Jin ZhouRapeseed Cultivation and Breeding Lab, Anhui Agricultural University, Hefei, China.
Anhui Agricultural University · CNQuaid-i-Azam University · PKUniversity of Faisalabad · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In several parts of the world, the prevalence and severity of drought are predicted to increase, creating considerable pressure on global agricultural yield. Among all abiotic stresses, drought is anticipated to produce the most substantial impact on soil biota and plants, along with complex environmental impacts on other ecological systems. Being sessile, plants tend to be the least resilient to drought-induced osmotic stress, which reduces nutrient accessibility due to soil heterogeneity and limits nutrient access to the root system. Drought tolerance is a complex quantitative trait regulated by multiple genes, and it is one of the most challenging characteristics to study and classify. Fortunately, the clustered regularly interspaced short palindromic repeat (CRISPR) technology has paved the way as a new frontier in crop improvement, thereby revolutionizing plant breeding. The application of CRISPER systems has proven groundbreaking across numerous biological fields, particularly in biomedicine and agriculture. The present review highlights the principle and optimization of CRISPR systems and their implementation for crop improvement, particularly in terms of drought tolerance, yield, and domestication. Furthermore, we address the ways in which innovative genome editing tools can help recognize and modify novel genes coffering drought tolerance. We anticipate the establishment of effective strategies of crop yield improvement in water-limited regions through collaborative efforts in the near future.

Indexed as

DroughtsAbscisic AcidCRISPR-Cas SystemsCrops, AgriculturalEthylenesGene EditingGenome, PlantOsmotic PressurePlants, Genetically ModifiedStress, PhysiologicalAbscisic AcidethyleneEthylenesABA regulationCRISPR–Cas9Droughtethylenegenome editingplant productivity

Identifiers

PMID34506262
PMCPMC8808358
OpenAlexW3198810747

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.