Evidence map›Paper›PMID 34510822›Full record

ArticleAdvanced healthcare materials2021

Stem/Proliferative and Differentiated Cells within Primary Murine Colonic Epithelium Display Distinct Intracellular Free Ca

Sebastian Mestril, Raehyun Kim, Samuel S Hinman, Shawn M Gomez, Nancy L Allbritton

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Store-Operated CaJournal of clinical medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sebastian MestrilJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, 27599, USA.
Raehyun KimDepartment of Bioengineering, University of Washington, Seattle, WA, 98195, USA.
Samuel S HinmanDepartment of Bioengineering, University of Washington, Seattle, WA, 98195, USA.
Shawn M GomezJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, 27599, USA.
Nancy L AllbrittonDepartment of Bioengineering, University of Washington, Seattle, WA, 98195, USA.ORCID 0000-0002-9242-768X
University of Washington · USUniversity of North Carolina at Chapel Hill · US

Funding

UNC Initiative for Maximizing Student DevelopmentR25GM055336 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COOK, JEANETTE GOWEN, KASH, THOMAS L. · 1996 to 2023
$12.1M
DEVELOPMENT OF HUMAN INTESTINAL SIMULACRAR01DK109559 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALLBRITTON, NANCY L., BULTMAN, SCOTT J · 2015 to 2019
$5.2M
Development of a microphysiologic system to assay the interaction of the human colonic epithelium on Clostridium difficileR01DK120606 · NIDDK · UNIVERSITY OF WASHINGTON · PI ALLBRITTON, NANCY L., SHEIKH, SHEHZAD Z. · 2020 to 2023
$2.2M
NIDDK NIH HHS R01 DK109559NIDDK NIH HHS R01 DK120606NIGMS NIH HHS R25 GM055336
6 · The paper itself

Abstract

The second messenger, intracellular free calcium (Ca

Indexed as

ColonIntestinal MucosaAnimalsCell DifferentiationEpitheliumMiceSignal TransductionCa2+colonhydrogelsintestineprimary cellsstiffness

Identifiers

PMID34510822
PMCPMC8599644
OpenAlexW3201106058

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.