ArticleJournal of clinical orthopaedics and trauma2021
18F-NaF simultaneous PET/MRI in osteoarthritis: Initial observations with case illustration.
Article in Journal of clinical orthopaedics and trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Entheseal bone remodeling and patient reported outcomes in osteoarthritis - A quantitative [18F]NaF-PET MRI study.Osteoarthritis and cartilage · 2025Observational
- Recent evolution in imaging techniques for assessment of synovitis in osteoarthritis.Skeletal radiology · 2025Review
- Role of Positron Emission Tomography (PET) in the Diagnosis of Musculoskeletal Disorders.Journal of clinical medicine · 2025Review
- Molecular imaging for evaluation of synovitis associated with osteoarthritis: a narrative review.Arthritis research & therapy · 2024Review
- Patterns of antibiotic resistance genes and virulence factor genes in the gut microbiome of patients with osteoarthritis and rheumatoid arthritis.Frontiers in microbiology · 2024Article
- Subchondral bone in knee osteoarthritis: bystander or treatment target?Skeletal radiology · 2023Review
- Updates of the imaging of musculoskeletal problems.Journal of clinical orthopaedics and trauma · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is a debilitating disease generally of old age manifested as degeneration of articular cartilage. With no definitive treatment available, ongoing research aims at early detection and use specific noninvasive imaging markers to monitor therapeutic efficacy of disease modifying osteoarthritic drug (DMOAD) to reverse or/and arrest the disease process. Articular cartilage degradation and loss, as well as bone remodelling, are typical biomarkers of OA. As a result, an ideal imaging technique for early detection of OA is required, which must be sensitive to both soft tissue and bone health. PET/MRI is emerging as an imaging tool which can be used to study the underlying pathogenesis of OA as it enables us to assess molecular activity with PET markers while also linking them to qualitative and quantitative MRI indices of OA. In this regard recent work was exploring the role of 18F-Na Fluoride which is a marker of bone remodelling together with MRI in early detection of OA on simultaneous PET/MRI. In this article we intend to present different patterns of OA (mild to severe stages of OA) that we had observed on 18F-Sodium Fluoride (18F-NaF) PET/MRI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.