Evidence map›Paper›PMID 34514749›Full record

ArticleObesity (Silver Spring, Md.)2021

Adverse generational changes in obesity development converge at midlife without increased cardiometabolic risk.

Dorina Ibi, M Liset Rietman, H S J Picavet, Jan Bert van Klinken, Ko Willems van Dijk, Martijn E T Dollé, W M Monique Verschuren

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dorina IbiLeiden University Medical Center, Leiden, the Netherlands.ORCID 0000-0003-0908-4039
M Liset RietmanNational Institute for Public Health and the Environment, Bilthoven, the Netherlands.
H S J PicavetNational Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Jan Bert van KlinkenLeiden University Medical Center, Leiden, the Netherlands.
Ko Willems van DijkLeiden University Medical Center, Leiden, the Netherlands.
Martijn E T DolléLeiden University Medical Center, Leiden, the Netherlands.
W M Monique VerschurenNational Institute for Public Health and the Environment, Bilthoven, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveObesity is becoming a global public health problem, but it is unclear how it impacts different generations over the life course. Here, a descriptive analysis of the age-related changes in anthropometric measures and related cardiometabolic risk factors across different generations was performed.

methodsThe development of anthropometric measures and related cardiometabolic risk factors was studied during 26 years of follow-up in the Doetinchem Cohort Study (N = 6,314 at baseline). All analyses were stratified by sex and generation, i.e., 10-year age groups (20-29, 30-39, 40-49, and 50-59 years) at baseline. Generalized estimating equations were used to test for generational differences.

resultsWeight, BMI, waist circumference, and prevalence of overweight and obesity were higher, in general, in the younger generations during the first 10 to 15 years of follow-up. From age 50 to 59 years onward, these measures converged in all generations of men and women. Among cardiometabolic risk factors, only type 2 diabetes showed an unfavorable shift between the two oldest generations of men.

conclusionsIt was observed that, compared with the older generations, the younger generations had obesity at an earlier age but did not reach higher levels at midlife and beyond. This increased exposure to obesity was not (yet) associated with increased prevalence of cardiometabolic risk factors.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2AdultBody Mass IndexCohort StudiesFemaleHumansMaleMiddle AgedObesityPrevalenceRisk FactorsWaist CircumferenceYoung Adult

Identifiers

PMID34514749
PMCPMC8597017

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.