Evidence map›Paper›PMID 34518755›Full record

ArticleSaudi journal of biological sciences2022

Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of

Shabir Ahmad Mir, Ahmad Firoz, Mohammed Alaidarous, Bader Alshehri, Abdul Aziz Bin Dukhyil, Saeed Banawas, Suliman A Alsagaby, Wael Alturaiki, Gulzar Ahmad Bhat, Faizan Kashoo and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Exploring the Therapeutic Potential ofMolecules (Basel, Switzerland) · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. Inhibitory Potential of theMolecules (Basel, Switzerland) · 2023
    Article
  7. Small molecules in the treatment of COVID-19.Signal transduction and targeted therapy · 2022
    Review
  8. Review
  9. Molecules (Basel, Switzerland) · 2022
    Review
  10. Biomolecules · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Shabir Ahmad MirDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Ahmad FirozDepartment of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Ssaudi Arabia.
Mohammed AlaidarousDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Bader AlshehriDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Abdul Aziz Bin DukhyilDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Saeed BanawasDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Suliman A AlsagabyDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Wael AlturaikiDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Gulzar Ahmad BhatDepartment of Clinical Biochemistry, Sher-i-Kashmir Institute of Medical Science, Srinagar, India.
Faizan KashooDepartment of Physical Therapy and Health Rehabilitation, College of Applied Medical Sciences, Majmaah University, Al Majmaah-11952, Saudi Arabia.
Ahmad M Abdel-HadiDepartment of Medical Laboratory Sciences, College of Applied Medical Science, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Majmaah University · SAAl-Azhar University · EGKing Abdulaziz University · SAOregon State University · USSher-i-Kashmir Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19), which emerged in December 2019, continues to be a serious health concern worldwide. There is an urgent need to develop effective drugs and vaccines to control the spread of this disease. In the current study, the main phytochemical compounds of

Indexed as

COVID-19, coronavirus disease 2019DockingDrugGUI, graphical user interfaceIn silicoMERS-CoV, Middle East respiratory syndrome coronavirusNigella SativaPhytochemicalRCSB PDB, Research Collaboratory for Structural Bioinformatics Protein Data BankRdRp, RNA-dependent RNA polymeraseRMSD, root mean square deviationRMSF, root mean square fluctuationsRNA polymeraseSARS-CoV-2SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2

Identifiers

PMID34518755
PMCPMC8426002
OpenAlexW3197967153

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.