Trial reportMicrobiology spectrum2021
Gut Microbiota Serves a Predictable Outcome of Short-Term Low-Carbohydrate Diet (LCD) Intervention for Patients with Obesity.
Trial report in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impacts of Lifestyle and Microbiota-Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Involvement of Intestinal Microbiota in Adult Neurogenesis and the Expression of Brain-Derived Neurotrophic Factor.International journal of molecular sciences · 2022Pooled it
- Impact of Food-Based Weight Loss Interventions on Gut Microbiome in Individuals with Obesity: A Systematic Review.Nutrients · 2022Pooled it
- Effects of healthy low-carbohydrate diet and time-restricted eating on weight and gut microbiome in adults with overweight or obesity: Feeding RCT.Cell reports. Medicine · 2024Trial
- Pasteurized Akkermansia muciniphila AKK PROBIO Attenuates Obesity Through Gut Microbiota-SCFA-GLP-1 Axis and Potential Involvement of AMPK/PPAR-α Pathway.Probiotics and antimicrobial proteins · 2026Article
- EasyMultiProfiler: an efficient multi-omics data integration and analysis workflow for microbiome research.Science China. Life sciences · 2026Article
- Gut microbiota orchestrates bone homeostasis: a multi-pathway network from intestine to skeleton.Frontiers in endocrinology · 2026Review
- The impact of low carbohydrate diet on the plasma proteomic profile of individuals with obesity.Frontiers in nutrition · 2026Article
- Association between a low-carbohydrate diet and macronutrient intake with the gut microbiome, and their interaction with dyslipidemia among Korean adults.Nutrition journal · 2025Article
- Machine learning based gut microbiota pattern and response to fiber as a diagnostic tool for chronic inflammatory diseases.BMC microbiology · 2025Article
- Multi-trajectories of BMI, waist circumference, gut microbiota, and incident dyslipidemia: a 27-year prospective study.mSystems · 2025Article
- Exploring correlation between preoperative gut microbiota and PONV using 16S absolute quantitative sequencing: a prospective observational study.Frontiers in medicine · 2025Article
- Traditional Mongolian Medicine Qiqirigan-8 alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism.Frontiers in microbiology · 2025Article
- Physicochemical properties and fermentation characteristics of a novel polysaccharide degraded fromFood chemistry: X · 2024Article
- Fecal Microbiota Transplantation Activity ofFoods (Basel, Switzerland) · 2024Article
- Effect of time-restricted eating regimen on weight loss is mediated by gut microbiome.iScience · 2024Article
- Dynamic changes in butyrate levels regulate satellite cell homeostasis by preventing spontaneous activation during aging.Science China. Life sciences · 2024Article
- Direct and Indirect Evidence of Effects ofInternational journal of molecular sciences · 2023Review
- Weight Loss Promotion in Individuals with Obesity through Gut Microbiota Alterations with a Multiphase Modified Ketogenic Diet.Nutrients · 2023Article
- White adipose tissue undergoes browning during preweaning period in association with microbiota formation in mice.iScience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To date, much progress has been made in dietary therapy for obese patients. A low-carbohydrate diet (LCD) has reached a revival in its clinical use during the past decade with undefined mechanisms and debatable efficacy. The gut microbiota has been suggested to promote energy harvesting. Here, we propose that the gut microbiota contributes to the inconsistent outcome under an LCD. To test this hypothesis, patients with obesity or patients who were overweight were randomly assigned to a normal diet (ND) or an LCD group with
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.