Evidence map›Paper›PMID 34523995›Full record

ArticleMicrobiology spectrum2021

Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging.

Joshua D Brycki, Jeremy R Chen See, Gillian R Letson, Cade S Emlet, Lavinia V Unverdorben, Nathan S Heibeck, Colin J Brislawn, Vincent P Buonaccorsi, Jason P Chan, Regina Lamendella

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Joshua D Brycki *Juniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Jeremy R Chen See *Juniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Gillian R LetsonJuniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Cade S EmletJuniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Lavinia V UnverdorbenJuniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Nathan S HeibeckJuniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Colin J BrislawnContamination Source Identification, Huntingdon, Pennsylvania, USA.
Vincent P BuonaccorsiJuniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Jason P ChanMarian University, Indianapolis, Indiana, USA.
Regina LamendellaJuniata Collegegrid.258264.f, Huntingdon, Pennsylvania, USA.
Juniata College · USMarian University - Indiana · USPrimary Source · US

Funding

The roles of sphingolipids in stress response and healthy aging.R15AG052933 · NIA · MARIAN UNIVERSITY · PI STAAB, TRISHA · 2016 to 2020
$662k
Analyses of host-microbiota interactions in aging C. elegans hostsR15AG063103 · NIA · JUNIATA COLLEGE · PI LAMENDELLA, REGINA · 2019 to 2019
$328k
NIA NIH HHS R15 AG052933NIA NIH HHS R15 AG063103
6 · The paper itself

Abstract

Host-bacterial interactions over the course of aging are understudied due to complexities of the human microbiome and challenges of collecting samples that span a lifetime. To investigate the role of host-microbial interactions in aging, we performed transcriptomics using wild-type Caenorhabditis elegans (

Indexed as

Gastrointestinal MicrobiomeAgingAnimalsCaenorhabditis elegansDisease Models, AnimalEscherichia coliEscherichia coli ProteinsFemaleHumansMaleTranscriptomeEscherichia coli ProteinsagingbacteriaCaenorhabditis elegansEscherichia colimicrobiometranscriptomics

Identifiers

PMID34523995
PMCPMC8557943
OpenAlexW3200134097

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.