Evidence map›Paper›PMID 34525867›Full record

SynthesisThe Australian and New Zealand journal of psychiatry2022

Non-response to psychotherapy for borderline personality disorder: A systematic review.

Jane Woodbridge, Michelle Townsend, Samantha Reis, Saniya Singh, Brin Fs Grenyer

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in The Australian and New Zealand journal of psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
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  4. Review
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  7. Positive Constructs in Schema Therapy: A Scoping Review.Journal of clinical psychology · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Psychosocial functioning in personality disorders.Borderline personality disorder and emotion dysregulation · 2025
    Review
  13. Article
  14. Article
  15. Using Case-Based Teaching: Does Our Dysregulated Hospitalized Patient Have Borderline Personality or Autism Spectrum Disorder?Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2025
    Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jane WoodbridgeIllawarra Health and Medical Research Institute and School of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Michelle TownsendIllawarra Health and Medical Research Institute and School of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Samantha ReisIllawarra Health and Medical Research Institute and School of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Saniya SinghIllawarra Health and Medical Research Institute and School of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Brin Fs GrenyerIllawarra Health and Medical Research Institute and School of Psychology, University of Wollongong, Wollongong, NSW, Australia.ORCID 0000-0003-1501-4336
University of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

highlightThis is the first systematic review to investigate non-response to psychotherapy for borderline personality disorder.

backgroundPsychotherapy is the recommended treatment for borderline personality disorder. While systematic reviews have demonstrated the effectiveness of psychotherapy for borderline personality disorder, effect sizes remain small and influenced by bias. Furthermore, the proportion of people who do not respond to treatment is seldom reported or analysed.

objectiveTo obtain an informed estimate of the proportion of people who do not respond to psychotherapy for borderline personality disorder.

methodsSystematic searches of five databases, PubMed, Web of Science, Scopus, PsycINFO and the Cochrane Library, occurred in November 2020. Inclusion criteria: participants diagnosed with borderline personality disorder, treated with psychotherapy and data reporting either (a) the proportion of the sample that experienced 'reliable change' or (b) the percentage of sample that no longer met criteria for borderline personality disorder at conclusion of therapy. Exclusion criteria: studies published prior to 1980 or not in English. Of the 19,517 studies identified, 28 met inclusion criteria.

resultsTwenty-eight studies were included in the review comprising a total of 2436 participants. Average treatment duration was 11 months using well-known evidence-based approaches. Approximately half did not respond to treatment; M = 48.80% (SD = 22.77). LIMITATIONS: Data regarding within sample variability and non-response are seldom reported. Methods of reporting data on dosage and comorbidities were highly divergent which precluded the ability to conduct predictive analyses. Other limitations include lack of sensitivity analysis, and studies published in English only.

conclusionResults of this review suggest that a large proportion of people are not responding to psychotherapy for borderline personality disorder and that factors relating to non-response are both elusive and inconsistently reported. Novel, tailored or enhanced interventions are needed to improve outcomes for individuals not responding to current established treatments.

Indexed as

Borderline Personality DisorderHumansPsychotherapyResearch Designborderline personality disorderNon-responsepoor responsepsychotherapy outcomestreatment failuretreatment outcomes

Identifiers

PMID34525867
PMCPMC9218414
OpenAlexW3200660882

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.