Evidence map›Paper›PMID 34527684›Full record

ArticleFrontiers in medicine2021

Clinical Significance and Integrative Analysis of the SMC Family in Hepatocellular Carcinoma.

Hui Nie, Yutong Wang, Xuejie Yang, Zhiming Liao, Xiaoyun He, Jianhua Zhou, Chunlin Ou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hui NieDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Yutong WangDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Xuejie YangDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Zhiming LiaoDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Xiaoyun HeDepartments of Ultrasound Imaging, Xiangya Hospital, Central South University, Changsha, China.
Jianhua ZhouDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Chunlin OuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, hepatocellular carcinoma (HCC) is one of the most malignant cancers with poor prognosis. The structural maintenance of chromosomes (SMC) gene family has been shown to play important roles in human cancers. Nevertheless, the role of SMC members in HCC is not well-understood. In this study, we comprehensively explored the role of the SMC family in HCC using a series of bioinformatic analysis tools. Studies have demonstrated that the mRNA expression levels of

Indexed as

biomarkerhepatocellular carcinomaimmune infiltrationmethylationSMC familytherapeutic target

Identifiers

PMID34527684
PMCPMC8437102
OpenAlexW3197381995

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.