Evidence map›Paper›PMID 34528255›Full record

ReviewJournal of anatomy2022

The structure of sensory afferent compartments in health and disease.

Steven J Middleton, Jimena Perez-Sanchez, John M Dawes

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of anatomy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Mechanisms of Action of Dorsal Root Ganglion Stimulation.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. A role for axon-glial interactions and Netrin-G1 signaling in the formation of low-threshold mechanoreceptor end organs.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Steven J MiddletonNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.ORCID 0000-0002-0708-7335
Jimena Perez-SanchezNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.ORCID 0000-0002-4967-5418
John M DawesNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.ORCID 0000-0003-4179-3492
University of Oxford · GB

Funding

Medical Research Council MR/T020113/1Medical Research Council MR/V003534/1
6 · The paper itself

Abstract

Primary sensory neurons are a heterogeneous population of cells able to respond to both innocuous and noxious stimuli. Like most neurons they are highly compartmentalised, allowing them to detect, convey and transfer sensory information. These compartments include specialised sensory endings in the skin, the nodes of Ranvier in myelinated axons, the cell soma and their central terminals in the spinal cord. In this review, we will highlight the importance of these compartments to primary afferent function, describe how these structures are compromised following nerve damage and how this relates to neuropathic pain.

Indexed as

Ganglia, SpinalSpinal CordAxonsNeuronsNeurons, Afferentcentral terminalscutaneous sensory endingsDRG neuronsDRG neuron somaneuronal compartmentsneuropathic painnode of Ranvierpainsensory afferents

Identifiers

PMID34528255
PMCPMC9558153
OpenAlexW3200943452

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.