Evidence map›Paper›PMID 34530907›Full record

ArticleBMC research notes2021

Transcriptome profiles of the skeletal muscle of mature cows during feed restriction and realimentation.

Hannah C Cunningham-Hollinger, Larry A Kuehn, Kristi M Cammack, Kristin E Hales, William T Oliver, Matthew S Crouse, Celine Chen, Harvey C Freetly, Amanda K Lindholm-Perry

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hannah C Cunningham-HollingerUniversity of Wyoming, Laramie, WY, 82071, USA.
Larry A KuehnUSDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, NE, 68933, USA.
Kristi M CammackSouth Dakota State University, West River Ag Center, Rapid City, SD, 57702, USA.
Kristin E HalesUSDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, NE, 68933, USA.
William T OliverUSDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, NE, 68933, USA.
Matthew S CrouseUSDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, NE, 68933, USA.
Celine ChenUSDA, ARS, Beltsville Human Nutrition Research Center, Beltsville, MD, 20705, USA.
Harvey C FreetlyUSDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, NE, 68933, USA.
Amanda K Lindholm-PerryUSDA, ARS, U.S. Meat Animal Research Center, P.O. Box 166, Clay Center, NE, 68933, USA. Amanda.lindholm@usda.gov.ORCID http://orcid.org/0000-0002-5555-118X
Roman L. Hruska U.S. Meat Animal Research Center · USBeltsville Human Nutrition Research Center · USSouth Dakota State University · USUniversity of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRealimentation can compensate for weight loss from poor-quality feedstuffs or drought. Mature cows fluctuate in body weight throughout the year due to nutrient availability. The objective of this study was to determine whether cows that differ in weight gain during realimentation also differ in the abundance of transcripts for enzymes associated with energy utilization in skeletal muscle. Mature cows were subjected to feed restriction followed by ad libitum feed. Skeletal muscle transcriptome expression differences during the two feeding periods were determined from cows with greater (n = 6) and less (n = 6) weight gain during the ad libitum feeding period.

resultsA total of 567 differentially expressed genes (408 up- and 159 down-regulated) were identified for the comparison of restriction and ad libitum periods (P

Indexed as

Animal FeedTranscriptomeAnimalsBody WeightCattleFemaleMuscle, SkeletalWeight GainBody weight gainMicroarraySkeletal muscleTranscriptome

Identifiers

PMID34530907
PMCPMC8447676
OpenAlexW3200530957

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.