Evidence map›Paper›PMID 34532617›Full record

ArticleJBMR plus2021

Independent External Validation of FRAX and Garvan Fracture Risk Calculators: A Sub-Study of the FRISBEE Cohort.

Felicia Baleanu, Laura Iconaru, Alexia Charles, Virginie Kinnard, Jean-François Fils, Michel Moreau, Rafik Karmali, Murielle Surquin, Florence Benoit, Aude Mugisha and 4 more

Abstract read
In one paragraph

Article in JBMR plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Revised Swedish FRAX models and the establishment of age-dependent intervention thresholds.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Selection for treatment of patients at high risk of fracture by the short versus long term prediction models - data from the Belgian FRISBEE cohort.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Article
  8. Article
  9. Article
  10. Predictive performance of the Garvan Fracture Risk Calculator: a registry-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Felicia BaleanuDepartment of Endocrinology, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.ORCID https://orcid.org/0000-0002-2774-8874
Laura IconaruDepartment of Endocrinology, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.
Alexia CharlesDepartment of Clinical Research, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.
Virginie KinnardDepartment of Geriatrics, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.ORCID https://orcid.org/0000-0001-5760-9325
Jean-François FilsArs Statistica Nivelles Belgium.
Michel MoreauData Centre, Institute Jules Bordet Université Libre de Bruxelles Brussels Belgium.
Rafik KarmaliDepartment of Endocrinology, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.
Murielle SurquinDepartment of Geriatrics, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.
Florence BenoitDepartment of Geriatrics, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.
Aude MugishaDepartment of Geriatrics, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.
Marianne PaesmansData Centre, Institute Jules Bordet Université Libre de Bruxelles Brussels Belgium.
Michaël R LaurentCentre for Metabolic Bone Diseases University Hospitals Leuven Leuven Belgium.ORCID https://orcid.org/0000-0001-9681-8330
Pierre BergmannDepartment of Nuclear Medicine, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.ORCID https://orcid.org/0000-0001-8998-8382
Jean-Jacques BodyDepartment of Endocrinology, CHU Brugmann Université Libre de Bruxelles Brussels Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probabilistic models including clinical risk factors with or without bone mineral density (BMD) have been developed to estimate the 5- or 10-year absolute fracture risk. We investigated the performance of the FRAX and Garvan tools in a well-characterized population-based cohort of 3560 postmenopausal, volunteer women, aged 60 to 85 years at baseline, included in the Fracture Risk Brussels Epidemiological Enquiry (FRISBEE) cohort, during 5 years of follow-up. Baseline data were used to calculate the estimated 10-year risk of hip and major osteoporotic fractures (MOFs) for each participant using FRAX (Belgium). We computed the 5-year risk according to the Garvan model with BMD. For calibration, the predicted risk of fracture was compared with fracture incidence across a large range of estimated fracture risks. The accuracy of the calculators to predict fractures was assessed using the area under the receiver operating characteristic curves (AUC). The FRAX tool was well calibrated for hip fractures (slope 1.09,

Indexed as

BMDDISCRIMINATIONFRACTUREOSTEOPOROSISRISK ASSESSMENTRISK FACTORSVALIDATION

Identifiers

PMID34532617
PMCPMC8441269

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.