Evidence map›Paper›PMID 34539381›Full record

ArticleFrontiers in aging neuroscience2021

Investigating Associations Between Inflammatory Biomarkers, Gray Matter, Neurofilament Light and Cognitive Performance in Healthy Older Adults.

Hollis C Karoly, Carillon J Skrzynski, Erin Moe, Angela D Bryan, Kent E Hutchison

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. CSF IL-6, GDF-15, GFAP and NfL levels in early Alzheimer disease: a pilot study.Therapeutic advances in neurological disorders · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. The Neurocognitive Effects of Cannabis Across the Lifespan.Current behavioral neuroscience reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hollis C KarolyInstitute for Cognitive Science, University of Colorado Boulder, Boulder, CO, United States.
Carillon J SkrzynskiDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, United States.
Erin MoeDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Angela D BryanDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, United States.
Kent E HutchisonInstitute for Cognitive Science, University of Colorado Boulder, Boulder, CO, United States.
University of Colorado Anschutz Medical Campus · USUniversity of Colorado Boulder · USColorado State University · US

Funding

Enhancing function in later life: Exercise and functional network connectivityR01AG043452 · NIA · UNIVERSITY OF COLORADO · PI BRYAN, ANGELA · 2014 to 2018
$2.9M
NIA NIH HHS R01 AG043452
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingcognitive functiongray matterIL-6neurofilament light (NfL)

Identifiers

PMID34539381
PMCPMC8446648
OpenAlexW3198576569

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.