ArticleAmerican journal of translational research2021
Effect of shenling baizhu powder on the serum TH1 cytokines of elderly patients with ulcerative colitis complicated by bloody purulent stool.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.
- Systematic review and network meta-analysis of integrated traditional Chinese and conventional medicine for ulcerative colitis.Frontiers in pharmacology · 2026Pooled it
- The effect of Chinese herbal formulas combined with metformin on modulating the gut microbiota in the amelioration of type 2 diabetes mellitus: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Gut microbiota and spleen-strengthening and dampness-dispelling therapies in obesity and related metabolic disorders: key mechanisms and therapeutic potential.Frontiers in pharmacology · 2026Review
- Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF-κB Pathway.Frontiers in pharmacology · 2022Article
- Traditional Chinese medicine prescription Shenling BaiZhu powder to treat ulcerative colitis: Clinical evidence and potential mechanisms.Frontiers in pharmacology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the role of Shenling Baizhu powder as an adjuvant therapy on the serum TH1 of elderly patients with ulcerative colitis complicated by bloody purulent stool.
methodsA total of 70 elderly patients with ulcerative colitis complicated by bloody purulent stool presenting to our hospital from June 2018 to October 2019 were enrolled and equally randomized. Patients were administered mesalazine enteric-coated tablets in the control group, and patients were additionally treated with Shenling Baizhu powder. The main clinical symptom scores, the relief of bloody purulent stool symptoms, and the serum TH1 levels before and after treatment as well as the clinical efficacy were compared in the two groups, and the ROC curve was plotted to analyze the value of serum TH1 cytokine in predicting disease recurrence.
resultsAfter treatment, the scores in the two groups were decreased significantly, and the decrease in the study group was significant (P < 0.05). The total effective rate in the study group (88.57%) was significantly higher than that of the control group (68.57%), and the response rate after treatment in the study group (85.71%) was significantly higher than that of the control group (62.86%). In the two groups, serum IL-2 and IFN-γ levels were decreased significantly before and after treatment, but the decrease in the study group was significant (P < 0.05). ROC analysis showed that the area under the curve (AUC) of IL-2 was 0.797, the maximum Jordan index was 0.573, the sensitivity was 61.10%, and the specificity was 96.20%. The AUC of IFN-γ was 0.794, the maximum Jordan index was 0.453, the sensitivity was 55.60%, and the specificity was 72.50%.
conclusionShenling Baizhu powder as an adjuvant therapy is a promising option for elderly patients with ulcerative colitis complicated by bloody purulent stool.
Indexed as
Identifiers
34540098PMC8430119W3201263985What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.