Evidence map›Paper›PMID 34545811›Full record

ArticleeLife2021

Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome.

Anitha P Govind, Okunola Jeyifous, Theron A Russell, Zola Yi, Aubrey V Weigel, Abhijit Ramaprasad, Luke Newell, William Ramos, Fernando M Valbuena, Jason C Casler and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 49 citations in OpenAlex.

  1. Airway secretory cells contain both a perinuclear Golgi ribbon and dispersed Golgi satellites.American journal of respiratory cell and molecular biology · 2026
    Article
  2. Sialylation in the nervous system: Functions and mechanisms.The Journal of biological chemistry · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. July in focus in HCB.Histochemistry and cell biology · 2025
    Article
  10. Article
  11. Mucins and Their Roles in Asthma.Immunological reviews · 2025
    Review
  12. Lysosomes' fallback strategies: more than just survival or death.Frontiers in cell and developmental biology · 2025
    Review
  13. The restricted N-glycome of neurons is programmed during differentiation.bioRxiv : the preprint server for biology · 2024
    Article
  14. Fiber-basedNeurophotonics · 2024
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Anitha P Govind *Department of Neurobiology, University of Chicago, Chicago, United States.ORCID 0000-0002-5890-2395
Okunola Jeyifous *Department of Neurobiology, University of Chicago, Chicago, United States.ORCID 0000-0002-4176-4694
Theron A RussellDepartment of Neurobiology, University of Chicago, Chicago, United States.
Zola YiDepartment of Neurobiology, University of Chicago, Chicago, United States.
Aubrey V WeigelJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0003-1694-4420
Abhijit RamaprasadDepartment of Neurobiology, University of Chicago, Chicago, United States.
Luke NewellDepartment of Neurobiology, University of Chicago, Chicago, United States.
William RamosDepartment of Neurobiology, University of Chicago, Chicago, United States.
Fernando M ValbuenaDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, United States.
Jason C CaslerDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, United States.ORCID 0000-0001-9742-9978
Jing-Zhi YanDepartment of Pharmacology, Northwestern University, Feinberg School of Medicine, Chicago, United States.
Benjamin S GlickDepartment of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, United States.ORCID 0000-0002-7921-1374
Geoffrey T SwansonDepartment of Pharmacology, Northwestern University, Feinberg School of Medicine, Chicago, United States.
Jennifer Lippincott-SchwartzJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0002-8601-3501
William N GreenDepartment of Neurobiology, University of Chicago, Chicago, United States.ORCID 0000-0003-2167-1391
University of Chicago · USHoward Hughes Medical Institute · USMarine Biological Laboratory · USNorthwestern University · USAgency for Science, Technology and Research · SG

Funding

Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
PET imaging of a4b2 nicotinic receptor upregulation and smoking cessationR01DA044760 · NIDA · UNIVERSITY OF CHICAGO · PI CHEN, CHIN-TU, GREEN, WILLIAM · 2017 to 2021
$3.8M
Integrative Training in the Neurobiology of Addictive BehaviorsT32DA043469 · NIDA · UNIVERSITY OF CHICAGO · PI Donald Hedeker, Xiaoxi Zhuang · 2017 to 2026
$3.8M
Dissecting the functions of yeast COPI - Resubmission 01R01GM104010 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S · 2013 to 2020
$3.2M
RNA methylation in synaptic plasticity and drug-seekingR01DA043361 · NIDA · UNIVERSITY OF CHICAGO · PI ZHUANG, XIAOXI · 2017 to 2021
$2.8M
Different components of nicotine-induced upregulation of nicotinic receptors - E. Hunpatin SupplementR01DA035430 · NIDA · UNIVERSITY OF CHICAGO · PI GREEN, WILLIAM · 2013 to 2017
$2.3M
Howard Hughes Medical InstituteNIDA NIH HHS R01 DA035430NIDA NIH HHS R01 DA043361NIDA NIH HHS R01 DA044760NIDA NIH HHS T32 DA043469NIGMS NIH HHS R01 GM104010NIGMS NIH HHS T32 GM007183
6 · The paper itself

Abstract

Activity-driven changes in the neuronal surface glycoproteome are known to occur with synapse formation, plasticity, and related diseases, but their mechanistic basis and significance are unclear. Here, we observed that

Indexed as

AnimalsAutoantigensCell ProliferationDendritesEndoplasmic ReticulumGlycosylationGolgi ApparatusHEK293 CellsHumansMembrane GlycoproteinsMembrane ProteinsNeuronsPolysaccharidesProteomeRatsReceptors, NicotinicAutoantigensGolgin subfamily A member 2Membrane GlycoproteinsMembrane ProteinsPolysaccharidesProteomeReceptors, Nicotiniccell biologyglycosylationGolgiGolgi satelliteshumanneuronal activityneurosciencenicotineratsialic acid

Identifiers

PMID34545811
PMCPMC8494481
OpenAlexW3200270776

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.