Evidence mapPaperPMID 34548082Full record

SynthesisNutrition journal2021

Prospective study of dietary mushroom intake and risk of mortality: results from continuous National Health and Nutrition Examination Survey (NHANES) 2003-2014 and a meta-analysis.

Djibril M Ba, Xiang Gao, Laila Al-Shaar, Joshua Muscat, Vernon M Chinchilli, Paddy Ssentongo, Xinyuan Zhang, Guodong Liu, Robert B Beelman, John P Richie

Abstract readMeta-Analysis
In one paragraph

Synthesis in Nutrition journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Djibril M BaDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Xiang GaoDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.
Laila Al-ShaarDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Joshua MuscatDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Vernon M ChinchilliDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Paddy SsentongoDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Xinyuan ZhangDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.
Guodong LiuDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA.
Robert B BeelmanDepartment of Food Science and Center for Plant and Mushroom Foods for Health, College of Agricultural Sciences, Pennsylvania State University, University Park, PA, USA.
John P RichieDepartment of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA. jrichie@pennstatehealth.psu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether mushroom consumption, which is a rich source of potent antioxidants ergothioneine and glutathione, vitamins, and minerals (e.g., selenium & copper), is associated with a lower mortality risk is not well understood. This study aimed to examine the association between mushroom consumption and risk of mortality in a prospective cohort study and a meta-analysis of prospective cohort studies.

methodsWe followed 30,378 participants from the continuous National Health and Nutrition Examination Survey (NHANES) extant data (2003-2014). Dietary mushroom intake was assessed using up to two 24-h recalls. Mortality was evaluated in all participants linked to the National Death Index mortality data through December 31, 2015. We used Cox proportional hazards regression models to calculate multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (95% CIs). We also conducted a meta-analysis, including results from our present study and 4 other cohort studies.

resultsDuring a mean (SD) of 6.7 (3.4) years of follow-up, a total of 2855 death cases were documented among NHANES participants. In our analysis of continuous NHANES, we found a non-significant association between mushroom consumption and all-cause mortality (adjusted hazard ratio (HR) = 0.84; 95% CI: 0.67-1.06) after adjusting for demographic, major lifestyle factors, overall diet quality, and other dietary factors, including total energy. The meta-analysis of prospective cohort studies, including 601,893 individuals, showed that mushroom consumption was associated with a lower risk of all-cause mortality (pooled risk ratio: 0.94; 95% CI: 0.91, 0.98).

conclusionIn a meta-analysis of prospective cohort studies, mushroom consumption was associated with a lower risk of all-cause mortality.

Indexed as

AgaricalesCardiovascular DiseasesCohort StudiesDietHumansMortalityNutrition SurveysProportional Hazards ModelsProspective StudiesRisk FactorsDietMeta-analysisMortality riskMushroomNHANESProspective study

Identifiers

PMID34548082
PMCPMC8454070

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.