Evidence map›Paper›PMID 34553252›Full record

ArticleEuropean journal of pediatrics2022

Kidney complications in 107 Fanconi anemia patients submitted to hematopoietic cell transplantation.

Mariana Munhoz da Cunha, Fellype Carvalho Barreto, Samantha Nichele, Joanna Trennepohl, Lisandro Ribeiro, Gisele Loth, Adriana Koliski, Tyane de Almeida Pinto Jardim, Adriana Mello, Ricardo Pasquini and 2 more

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In one paragraph

Article in European journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Mariana Munhoz da CunhaPediatric Nephrology, Federal University of Paraná, Curitiba, PR, Brazil. mamcunha@hotmail.com.ORCID http://orcid.org/0000-0002-8901-5553
Fellype Carvalho BarretoDepartment of Internal Medicine, Service of Nephrology, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-6394-9227
Samantha NicheleBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0003-3857-2306
Joanna TrennepohlBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-5080-9364
Lisandro RibeiroBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0003-2938-5146
Gisele LothBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0003-2378-5026
Adriana KoliskiBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0001-7521-8766
Tyane de Almeida Pinto JardimPostgraduate Program in Internal Medicine and Health Science, Federal University of Parana, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-2104-2897
Adriana MelloBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-1971-9299
Ricardo PasquiniBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-9272-1061
Lucimary de Castro SylvestrePediatric Nephrology, Hospital Pequeno Príncipe, Rua Desembargador Motta, Curitiba, PR, 107080250-060, Brazil.ORCID http://orcid.org/0000-0002-6719-6509
Carmem BonfimBone Marrow Transplantation Unit, Federal University of Paraná, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0003-0343-2610
Universidade Federal do Paraná · BRHospital Erasto Gaertner · BRHospital IPO · BRPontifícia Universidade Católica do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fanconi anemia (FA) is a rare disease characterized by progressive bone marrow failure, cancer predisposition, and multiple systemic malformations, including congenital abnormalities of the kidney and urinary tract (CAKUT). Hematopoietic cell transplantation (HCT), the only potentially curative treatment for the hematological complications of FA, may precipitate acute kidney injury (AKI) and hypertension. We retrospectively investigated 107 FA patients who underwent HCT between 2009 and 2017. We investigated the incidence and risk factors of AKI within 100 days after HCT in a cohort of FA patients, and kidney function and hypertension over 2-year follow-up.The incidence of AKI (mainly stage I) was 18.7%. Patients aged ≥ 11 years at transplantation showed a higher risk of AKI (OR 3.53). The eGFR was 60-90 mL/min/1.73 m

Indexed as

Acute Kidney InjuryFanconi AnemiaHematopoietic Stem Cell TransplantationChildHumansKidneyRetrospective StudiesAcute kidney injuryCAKUTFanconi anemiaHematopoietic cell transplantationHypertension

Identifiers

PMID34553252
OpenAlexW3201383187

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.