Evidence map›Paper›PMID 34555359›Full record

ArticleBiophysical journal2021

Vectorial insertion of a β-helical peptide into membrane: a theoretical study on polytheonamide B.

Mahroof Kalathingal, Takashi Sumikama, Shigetoshi Oiki, Shinji Saito

Open access · greenAbstract read
In one paragraph

Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mahroof KalathingalSchool of Physical Sciences, The Graduate University for Advanced Studies, Okazaki, Japan.
Takashi SumikamaPRESTO, JST, Kawaguchi, Japan; Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kanazawa, Japan.
Shigetoshi OikiBiomedical Imaging Research Center, University of Fukui, Fukui, Japan. Electronic address: oiki@u-fukui.ac.jp.
Shinji SaitoSchool of Physical Sciences, The Graduate University for Advanced Studies, Okazaki, Japan; Institute for Molecular Science, Okazaki, Japan. Electronic address: shinji@ims.ac.jp.
The Graduate University for Advanced Studies, SOKENDAI · JPKanazawa University · JPUniversity of Fukui · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous unidirectional, or vectorial, insertion of transmembrane peptides is a fundamental biophysical process for toxin and viral actions. Polytheonamide B (pTB) is a potent cytotoxic peptide with a β

Indexed as

Intracellular Signaling Peptides and ProteinsPeptidesMembranesMolecular Dynamics SimulationIntracellular Signaling Peptides and ProteinsPeptidespolytheonamide B

Identifiers

PMID34555359
PMCPMC8595747
OpenAlexW3201178923

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.