Evidence map›Paper›PMID 34555524›Full record

ArticleJournal of cardiac failure2022

Noninvasive Venous Waveform Analysis Correlates With Pulmonary Capillary Wedge Pressure and Predicts 30-Day Admission in Patients With Heart Failure Undergoing Right Heart Catheterization.

Bret Alvis, Jessica Huston, Jeffery Schmeckpeper, Monica Polcz, Marisa Case, Rene Harder, Jonathan S Whitfield, Kendall G Spears, Meghan Breed, Lexie Vaughn and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. [Research progress on the early warning of heart failure based on remote dynamic monitoring technology].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Bret AlvisDepartment of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee; VoluMetrix, LLC, Nashville, Tennessee. Electronic address: bret.d.alvis@vumc.org.
Jessica HustonDepartment of Medicine, Division of Cardiovascular Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Jeffery SchmeckpeperDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Monica PolczDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Marisa CaseDepartment of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee.
Rene HarderVoluMetrix, LLC, Nashville, Tennessee.
Jonathan S WhitfieldVoluMetrix, LLC, Nashville, Tennessee.
Kendall G SpearsUniversity of Tennessee, Knoxville, Tennessee.
Meghan BreedDepartment of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Lexie VaughnDepartment of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Colleen BrophyVoluMetrix, LLC, Nashville, Tennessee; Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Kyle M HockingDepartment of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee; VoluMetrix, LLC, Nashville, Tennessee; Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Joann LindenfeldDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Vanderbilt University Medical Center · USVanderbilt University · USUniversity of Pittsburgh Medical Center · USUniversity of Tennessee at Knoxville · US

Funding

Non-Invasive Venous Waveform Analysis (NIVA) in patients with Heart Failure (HF)R44HL140669 · NHLBI · VOLUMETRIX, LLC · PI HOCKING, KYLE MITCHELL, LINDENFELD, JOANN · 2018 to 2025
$5.1M
Venous Waveform Analysis to Predict Volume OverloadR01HL148244 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Bret D. Alvis · 2019 to 2026
$3.4M
NHLBI NIH HHS R01 HL148244NHLBI NIH HHS R44 HL140669
6 · The paper itself

Abstract

backgroundHeart failure is the leading cause of hospitalization in the elderly and readmission is common. Clinical indicators of congestion may not precede acute congestion with enough time to prevent hospital admission for heart failure. Thus, there is a large and unmet need for accurate, noninvasive assessment of congestion. Noninvasive venous waveform analysis in heart failure (NIVA METHODS AND

resultsThe prototype NIVA

conclusionsThe NIVA

Indexed as

Heart FailureAgedCardiac CatheterizationHospitalizationHumansPredictive Value of TestsPulmonary Wedge PressureCongestionheart failurePCWPreadmissionvenous waveform

Identifiers

PMID34555524
PMCPMC8934313
OpenAlexW3201034745

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.