Evidence map›Paper›PMID 34558652›Full record

ReviewOncology reports2021

Bile reflux and hypopharyngeal cancer (Review).

Dimitra P Vageli, Sotirios G Doukas, Panagiotis G Doukas, Benjamin L Judson

Open access · hybridAbstract readReview
In one paragraph

Review in Oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Pilot study evaluating salivary bile acids as a diagnostic biomarker of laryngopharyngeal reflux.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Article
  9. Article
  10. Review article: Diagnosis and management of laryngopharyngeal reflux.Alimentary pharmacology & therapeutics · 2024
    Review
  11. [Characteristics performance of laryngopharyngeal reflux in narrow band imaging].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Bile reflux alters the profile of the gastric mucosa microbiota.Frontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitra P VageliThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Sotirios G DoukasThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Panagiotis G DoukasThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.
Benjamin L JudsonThe Yale Larynx Laboratory, Department of Surgery, Yale School of Medicine, New Haven, CT 06510, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laryngopharyngeal reflux, a variant of gastroesophageal reflux disease, has been considered a risk factor in the development of hypopharyngeal cancer. Bile acids are frequently present in the gastroesophageal refluxate and their effect has been associated with inflammatory and neoplastic changes in the upper aerodigestive tract. Recent

Indexed as

Bile Acids and SaltsBile RefluxCarcinoma, Squamous CellDNA DamageHumansHypopharyngeal NeoplasmsNF-kappa BRisk FactorsRNA, MessengerSignal TransductionSTAT3 Transcription FactorTumor Suppressor Protein p53Bile Acids and SaltsNF-kappa BRNA, MessengerSTAT3 protein, humanSTAT3 Transcription FactorTumor Suppressor Protein p53bile refluxconjugated bile acidsdeoxycholic acidDNA damagehead and neck cancerhypopharyngeal cancer; hypopharyngeal squamous cell carcinomain vivolaryngopharyngeal refluxNF‑κB

Identifiers

PMID34558652
PMCPMC8485019
OpenAlexW3201093904

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.