Evidence map›Paper›PMID 34562065›Full record

ArticleJournal of cellular and molecular medicine2021

Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.

Yu Sun, Linxue Zhang, Baoling Lu, Jingchen Wen, Mengyi Wang, Shiwu Zhang, Qianzhu Li, Feng Shu, Fangping Lu, Ning Liu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. HFrontiers in cell and developmental biology · 2026
    Review
  6. Review
  7. Protective Role of HDiabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Exogenous HJournal of cachexia, sarcopenia and muscle · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Advances of HAntioxidants (Basel, Switzerland) · 2023
    Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Yu SunDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Linxue ZhangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Baoling LuDepartment of Infectious, The Fourth Hospital of Harbin Medical University, Harbin, China.
Jingchen WenDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Mengyi WangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Shiwu ZhangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Qianzhu LiDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Feng ShuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Fangping LuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Ning LiuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Shuo PengDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Yajun ZhaoDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Shiyun DongDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Fanghao LuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Weihua ZhangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.ORCID 0000-0002-4165-5260
Yan WangDepartment of Urologic Surgery, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulation of lipid droplets (LDs) induces cardiac dysfunctions in type 2 diabetes patients. Recent studies have shown that hydrogen sulphide (H

Indexed as

AnimalsBiomarkersDiabetes Mellitus, Type 2Diabetic CardiomyopathiesDisease Models, AnimalEchocardiographyFemaleHeart Function TestsHydrogen SulfideHyperglycemiaHyperlipidemiasLipid DropletsLipid MetabolismMaleMiceMice, KnockoutBiomarkersHydrogen SulfideProteomeSyvn1 protein, mouseUbiquitin-Protein LigasesDGATdiabetic cardiomyopathyHrd1hydrogen sulphideLipid dropletsS-sulfhydration

Identifiers

PMID34562065
PMCPMC8500968
OpenAlexW3201113449

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.