ReviewMetabolites2021
Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification.
Review in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
108 citing papers in PubMed, 1 synthesis or guideline pooled it, 256 citations in OpenAlex.
- Functional annotation and meta-analysis of maize transcriptomes reveal genes involved in biotic and abiotic stress.BMC genomics · 2024Pooled it
- Frost Tolerance Under Cold Flooding Involves the Presence of Specific PR Proteins and Is Linked to Snow Mould Pathogen Resistance.International journal of molecular sciences · 2026Article
- Integrated Physiological and Multi-Omics Analysis Reveals Selenium-Mediated Drought Tolerance inInternational journal of molecular sciences · 2026Article
- Effects of Selenomethionine Supplementation on Tomato Fruit Quality and Yield Under Deficit Irrigation.International journal of molecular sciences · 2026Article
- The Circadian Oscillator Affects Both Glutathione Homeostasis and Its Response to Salt Stress in Arabidopsis thaliana.Plant, cell & environment · 2026Article
- Review
- Ion-structured transcriptional network reorganization is associated with tissue-specific adaptation to saline-alkaline stress in sorghum.BMC plant biology · 2026Article
- Chitosan-Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Functional Genomics of Sulfur Metabolism in Rice: Insights From Transgenic and MicroRNA-Based Strategies.Plant direct · 2026Review
- Distinct rhizosphere microbiomes and metabolomes mediate Fusarium crown rot resistance across wheat cultivars.NPJ biofilms and microbiomes · 2026Article
- CcAbl1 is required for virulence via regulating NADPH-glutathione-mediated redox balance in Cytospora chrysosperma.Stress biology · 2026Article
- Decoding core molecular mechanisms of heat-stress tolerance in Brassica napus using transcriptomics and machine learning.Plant cell reports · 2026Article
- Review
- Article
- Uncovering the potential MTAs, candidate genes and microRNAs regulatory networks involved in salinity stress tolerance triggered in Iranian Aegilops tauschii.Scientific reports · 2026Article
- Brassinolide Alleviates Maize Silk Growth Under Water Deficit by Reprogramming Sugar Metabolism and Enhancing Antioxidant Defense.Plants (Basel, Switzerland) · 2026Article
- Drought tolerance in soybean: genetics, metabolomics, remote sensing, and breeding for enhanced drought tolerance.Frontiers in plant science · 2026Review
- Empowering resilience: celebrating and accelerating women's transformative contributions to plant abiotic stress research (2010-2025).Frontiers in plant science · 2026Review
- Crosstalk between glutathione and melatonin in chromium detoxification in sweet potato revealed by high-throughput sequencing and physio-biochemical profiling.Frontiers in plant science · 2026Article
- Postharvest senescence of green vegetables and the role of glutathione metabolism: current state of knowledge and future research opportunities.Frontiers in plant science · 2026Review
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Glutathione is an essential metabolite for plant life best known for its role in the control of reactive oxygen species (ROS). Glutathione is also involved in the detoxification of methylglyoxal (MG) which, much like ROS, is produced at low levels by aerobic metabolism under normal conditions. While several physiological processes depend on ROS and MG, a variety of stresses can dramatically increase their concentration leading to potentially deleterious effects. In this review, we examine the structure and the stress regulation of the pathways involved in glutathione synthesis and degradation. We provide a synthesis of the current knowledge on the glutathione-dependent glyoxalase pathway responsible for MG detoxification. We present recent developments on the organization of the glyoxalase pathway in which alternative splicing generate a number of isoforms targeted to various subcellular compartments. Stress regulation of enzymes involved in MG detoxification occurs at multiple levels. A growing number of studies show that oxidative stress promotes the covalent modification of proteins by glutathione. This post-translational modification is called
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.