Evidence map›Paper›PMID 34564611›Full record

ReviewToxins2021

Bee Venom Acupuncture Effects on Pain and Its Mechanisms: An Updated Review.

Soo-Hyun Sung, Gihyun Lee

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Effectiveness of bee venom acupuncture for patients suffering from periarthritis humeroscapularis.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Soo-Hyun SungDepartment of Policy Development, National Development Institute of Korean Medicine, Seoul 04554, Korea.ORCID 0000-0001-7606-0147
Gihyun LeeCollege of Korean Medicine, Dongshin University, Naju 58245, Korea.ORCID 0000-0001-6250-8852
Dongshin University · KRNational Development Institute of Korean Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bee venom (BV) is a complex natural toxin that contains various pharmaceutical compounds. Bee venom acupuncture (BVA), involving a BV injection into a certain acupuncture point, has been utilized to relieve a range of pain conditions. Regardless of whether pain is caused by disease or injury, if not effectively treated, pain can exert a detrimental effect on all aspects of life. In the past decade, many researchers have investigated the anti-nociceptive effects of BVA through clinical use and experimental evaluation. This report reviews the existing knowledge on the analgesic effects of BVA, focusing on musculoskeletal pain, inflammatory pain and neuropathic pain, and its analgesic mechanisms. Although further clinical trials are needed to clinical application of experimental results, this review will contribute to the standardization and generalization of BVA.

Indexed as

Acupuncture TherapyAnalgesicsAnimalsBee VenomsHumansHyperalgesiaNeuralgiaAnalgesicsBee Venomsbee venombee venom acupuncturecomplementary and alternative medicineinflammatory painmusculoskeletal painneuropathic paintraditional

Identifiers

PMID34564611
PMCPMC8472865
OpenAlexW3197720639

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.