Evidence map›Paper›PMID 34566630›Full record

ReviewFrontiers in pharmacology2021

Novel Methods and Approaches for Safety Evaluation of Nanoparticle Formulations: A Focus Towards

Mounika Gayathri Tirumala, Pratibha Anchi, Susmitha Raja, Mahesh Rachamalla, Chandraiah Godugu

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

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  15. Nano-structured strategies in combatting neurodegeneration.Frontiers in bioengineering and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mounika Gayathri TirumalaDepartment of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India.
Pratibha AnchiDepartment of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India.
Susmitha RajaDepartment of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India.
Mahesh RachamallaDepartment of Biology, University of Saskatchewan, Saskatoon, SK, Canada.
Chandraiah GoduguDepartment of Regulatory Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotoxicology is an emerging field employed in the assessment of unintentional hazardous effects produced by nanoparticles (NPs) impacting human health and the environment. The nanotoxicity affects the range between induction of cellular stress and cytotoxicity. The reasons so far reported for these toxicological effects are due to their variable sizes with high surface areas, shape, charge, and physicochemical properties, which upon interaction with the biological components may influence their functioning and result in adverse outcomes (AO). Thus, understanding the risk produced by these materials now is an important safety concern for the development of nanotechnology and nanomedicine. Since the time nanotoxicology has evolved, the methods employed have been majorly relied on

Indexed as

in vitro assaynanomedicinenanoparticlesnanotechnologynanotoxicity assessment

Identifiers

PMID34566630
PMCPMC8458898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.