Evidence mapPaperPMID 34571842Full record

SynthesisCells2021

Therapeutic Potential of Complementary and Alternative Medicines in Peripheral Nerve Regeneration: A Systematic Review.

Yoon-Yen Yow, Tiong-Keat Goh, Ke-Ying Nyiew, Lee-Wei Lim, Siew-Moi Phang, Siew-Huah Lim, Shyamala Ratnayeke, Kah-Hui Wong

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Malaysian brown macroalgaIranian journal of basic medical sciences · 2023
    Article
  11. Metabolites ofMetabolites · 2022
    Article
  12. Review
  13. Review
  14. Peripheral Nerve Injury Treatments and Advances: One Health Perspective.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yoon-Yen YowDepartment of Biological Sciences, School of Medicine and Life Sciences, Sunway University, Petaling Jaya 47500, Malaysia.ORCID 0000-0002-3859-2094
Tiong-Keat GohDepartment of Biological Sciences, School of Medicine and Life Sciences, Sunway University, Petaling Jaya 47500, Malaysia.ORCID 0000-0002-3183-6244
Ke-Ying NyiewDepartment of Biological Sciences, School of Medicine and Life Sciences, Sunway University, Petaling Jaya 47500, Malaysia.
Lee-Wei LimNeuromodulation Laboratory, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, L4 Laboratory Block, Hong Kong.ORCID 0000-0001-6692-6285
Siew-Moi PhangInstitute of Ocean and Earth Sciences, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Siew-Huah LimDepartment of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Shyamala RatnayekeDepartment of Biological Sciences, School of Medicine and Life Sciences, Sunway University, Petaling Jaya 47500, Malaysia.
Kah-Hui WongDepartment of Anatomy, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0001-5669-8987
Sunway University · MYUniversity of Malaya · MYUniversity of Hong Kong · HK

Funding

Fundamental Research Grant Scheme from the Ministry of Higher Education Malaysia FRGS/1/2019/STG05/SYUC/02/1
6 · The paper itself

Abstract

Despite the progressive advances, current standards of treatments for peripheral nerve injury do not guarantee complete recovery. Thus, alternative therapeutic interventions should be considered. Complementary and alternative medicines (CAMs) are widely explored for their therapeutic value, but their potential use in peripheral nerve regeneration is underappreciated. The present systematic review, designed according to guidelines of Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols, aims to present and discuss the current literature on the neuroregenerative potential of CAMs, focusing on plants or herbs, mushrooms, decoctions, and their respective natural products. The available literature on CAMs associated with peripheral nerve regeneration published up to 2020 were retrieved from PubMed, Scopus, and Web of Science. According to current literature, the neuroregenerative potential of

Indexed as

AnimalsBiological ProductsComplementary TherapiesHumansNerve RegenerationPeripheral Nerve InjuriesPeripheral NervesSignal TransductionBiological Productscomplementary and alternative medicinesfunctional recoverynatural productsnerve regenerationnerve repairperipheral nerve injury

Identifiers

PMID34571842
PMCPMC8472132
OpenAlexW3195951031

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.