Evidence map›Paper›PMID 34572007›Full record

ReviewCells2021

Effects of High Dietary Carbohydrate and Lipid Intake on the Lifespan of

Berenice Franco-Juárez, Saúl Gómez-Manzo, Beatriz Hernández-Ochoa, Noemi Cárdenas-Rodríguez, Roberto Arreguin-Espinosa, Verónica Pérez de la Cruz, Daniel Ortega-Cuellar

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Postbiotic pA1cInternational journal of molecular sciences · 2025
    Article
  4. Black mulberry (Heliyon · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. International journal of molecular sciences · 2022
    Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Berenice Franco-JuárezDepartamento de Neurodesarrollo y Fisiología, División de Neurociencias, Instituto de Fisiología Celular, UNAM, Ciudad de México 04510, Mexico.ORCID 0000-0001-9633-0001
Saúl Gómez-ManzoLaboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, Ciudad de México 04530, Mexico.ORCID 0000-0003-2095-9182
Beatriz Hernández-OchoaLaboratorio de Inmunoquímica, Hospital Infantil de México Federico Gómez, Secretaría de Salud, Ciudad de México 06720, Mexico.ORCID 0000-0003-3939-6930
Noemi Cárdenas-RodríguezLaboratorio de Neurociencias, Instituto Nacional de Pediatría, Secretaría de Salud, Ciudad de México 04530, Mexico.ORCID 0000-0002-6580-3440
Roberto Arreguin-EspinosaDepartamento de Química de Biomacromoléculas, Instituto de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0002-4611-4770
Verónica Pérez de la CruzNeurochemistry and Behavior Laboratory, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Ciudad de México 14269, Mexico.ORCID 0000-0002-1451-8754
Daniel Ortega-CuellarLaboratorio de Nutrición Experimental, Instituto Nacional de Pediatría, Secretaría de Salud, Ciudad de México 04530, Mexico.ORCID 0000-0001-7950-4911
Secretaria de Salud · MXInstituto Nacional de Cardiología · MXInstituto Nacional de Neurología y Neurocirugía · MXUniversidad Nacional Autónoma de México · MX

Funding

Instituto Nacional de Pediatria 039/2018 and 041/2018
6 · The paper itself

Abstract

Health and lifespan are influenced by dietary nutrients, whose balance is dependent on the supply or demand of each organism. Many studies have shown that an increased carbohydrate-lipid intake plays a critical role in metabolic dysregulation, which impacts longevity.

Indexed as

AgingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDietDietary CarbohydratesHumansLipidsLongevityCaenorhabditis elegans ProteinsDietary CarbohydratesLipidscarbohydrateC. eleganslifespanlipidstranscription factors and metabolism

Identifiers

PMID34572007
PMCPMC8465757
OpenAlexW3198180936

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.