Evidence map›Paper›PMID 34572332›Full record

ArticleBiomedicines2021

Effective Accentuation of Voltage-Gated Sodium Current Caused by Apocynin (4'-Hydroxy-3'-methoxyacetophenone), a Known NADPH-Oxidase Inhibitor.

Tzu-Hsien Chuang, Hsin-Yen Cho, Sheng-Nan Wu

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Inhibition of Voltage-Gated NaInternational journal of molecular sciences · 2023
    Article
  5. Rufinamide, a Triazole-Derived Antiepileptic Drug, Stimulates CaInternational journal of molecular sciences · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Activation of Voltage-Gated NaBiomedicines · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tzu-Hsien ChuangDepartment of Physiology, National Cheng Kung University Medical College, No. 1, University Road, Tainan 70101, Taiwan.
Hsin-Yen ChoDepartment of Physiology, National Cheng Kung University Medical College, No. 1, University Road, Tainan 70101, Taiwan.
Sheng-Nan WuDepartment of Physiology, National Cheng Kung University Medical College, No. 1, University Road, Tainan 70101, Taiwan.ORCID 0000-0002-5208-3253
National Cheng Kung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apocynin (

Indexed as

apocynin (4′-Hydroxy-3′-methoxyacetophenone)current kineticselectrically excitable cellerg-mediated K+ currentNADPH-dependent oxidase (NOX)persistent Na+ currentvoltage-dependent hysteresisvoltage-gated Na+ current

Identifiers

PMID34572332
PMCPMC8464932
OpenAlexW3197379488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.