Evidence mapPaperPMID 34573073Full record

ReviewAntioxidants (Basel, Switzerland)2021

Antioxidants Present in Reproductive Tract Fluids and Their Relevance for Fertility.

João C Ribeiro, Patrícia C Braga, Ana D Martins, Branca M Silva, Marco G Alves, Pedro F Oliveira

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Oxidative Stress and Male Reproductive Health-First Edition.Antioxidants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Open veterinary journal · 2026
    Article
  10. Article
  11. Review
  12. Impact of Oxidative Stress and Antioxidants on Semen Quality in Dogs.Animals : an open access journal from MDPI · 2025
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Androgen Signaling in Prostate Cancer: When a Friend Turns Foe.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

João C RibeiroDepartment of Anatomy, Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0003-1461-8875
Patrícia C BragaDepartment of Anatomy, Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal.
Ana D MartinsQOPNA & LAQV, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Branca M SilvaCICS, Faculty of Health Sciences, University of Beira Interior, 6201-001 Covilhã, Portugal.ORCID 0000-0002-5610-8024
Marco G AlvesDepartment of Anatomy, Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal.ORCID 0000-0001-7635-783X
Pedro F OliveiraQOPNA & LAQV, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4989-5699

Funding

Fundação para a Ciência e a Tecnologia CEECINST/00026/2018Fundação para a Ciência e a Tecnologia UI/BD/150749/2020Fundação para a Ciência e a Tecnologia UI/BD/150750/2020Fundação para a Ciência e a Tecnologia UIDB/00215/2020Fundação para a Ciência e a Tecnologia UIDB/50006/2020Fundação para a Ciência e a Tecnologia UIDP/00215/2020
6 · The paper itself

Abstract

Nowadays, infertility is classified as a disease of the reproductive system. Although it does not compromise the life of the individual, it can have detrimental effects on the physiological and psychological health of the couple. Male fertility evaluation is mainly focused on the analysis of sperm parameters. However, the ejaculated fluid is also composed of seminal plasma, and the study of this fluid can provide crucial information to help in the assessment of male fertility status. Total antioxidant capacity of the seminal plasma has been positively correlated with the fertility of men. Moreover, evidence highlights to a similar importance as that of female reproductive tract fluid antioxidant capabilities and female fertility. Herein, we describe the functions of seminal plasma and female reproductive tract fluids, as well as their main antioxidant components and their relationships with fertility outcomes. Additionally, this review contains the most up to date information regarding the mechanisms of the interaction between the male and the female reproductive fluids and the importance of proper antioxidant capacity for fertilization.

Indexed as

antioxidantsfemale reproductive fluidfertility couplereactive oxygen speciesseminal plasmasperm parameters

Identifiers

PMID34573073
PMCPMC8466935

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.