Evidence map›Paper›PMID 34574146›Full record

ArticleFoods (Basel, Switzerland)2021

4-Hydroxyderricin Promotes Apoptosis and Cell Cycle Arrest through Regulating PI3K/AKT/mTOR Pathway in Hepatocellular Cells.

Xiang Gao, Yuhuan Jiang, Qi Xu, Feng Liu, Xuening Pang, Mingji Wang, Qun Li, Zichao Li

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Review
  6. Anticancer Potential of Natural Chalcones: In Vitro and In Vivo Evidence.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Protective Effect ofFoods (Basel, Switzerland) · 2022
    Article
  12. Bellidifolin fromToxicology reports · 2022
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiang GaoInstitute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China.
Yuhuan JiangInstitute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China.
Qi XuInstitute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China.
Feng LiuDepartment of Horticultural Technology, Ningbo City College of Vocational Technology, Ningbo 315199, China.
Xuening PangInstitute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China.
Mingji WangJoint Institute of Angelica keiskei Health Industry Technology, Qingdao University, Qingdao 266071, China.
Qun LiJoint Institute of Angelica keiskei Health Industry Technology, Qingdao University, Qingdao 266071, China.ORCID 0000-0003-0532-105X
Zichao LiInstitute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China.ORCID 0000-0003-2582-3006
Qingdao University · CN

Funding

Joint Institute of Angelica keiskei Health Industry Technology NoneNatural Science Foundation of Shandong Province ZR2019PH020
6 · The paper itself

Abstract

4-hydroxyderricin (4-HD), as a natural flavonoid compound derived from

Indexed as

Angelica keiskeianti-tumorapoptosiscell cyclechalconemechanism

Identifiers

PMID34574146
PMCPMC8468691
OpenAlexW3197631754

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.