Evidence map›Paper›PMID 34575237›Full record

ReviewJournal of clinical medicine2021

Neural Correlates of Aberrant Salience and Source Monitoring in Schizophrenia and At-Risk Mental States-A Systematic Review of fMRI Studies.

Joachim Kowalski, Adrianna Aleksandrowicz, Małgorzata Dąbkowska, Łukasz Gawęda

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joachim KowalskiExperimental Psychopathology Lab, Institute of Psychology, Polish Academy of Sciences, ul. Jaracza 1, 00-378 Warsaw, Poland.ORCID 0000-0001-6281-7401
Adrianna AleksandrowiczExperimental Psychopathology Lab, Institute of Psychology, Polish Academy of Sciences, ul. Jaracza 1, 00-378 Warsaw, Poland.
Małgorzata DąbkowskaExperimental Psychopathology Lab, Institute of Psychology, Polish Academy of Sciences, ul. Jaracza 1, 00-378 Warsaw, Poland.
Łukasz GawędaExperimental Psychopathology Lab, Institute of Psychology, Polish Academy of Sciences, ul. Jaracza 1, 00-378 Warsaw, Poland.
Institute of Psychology · PL

Funding

Narodowe Centrum Nauki 2019/35/O/HS6/02982Narodowe Centrum Nauki 2020/36/C/HS6/00420
6 · The paper itself

Abstract

Cognitive biases are an important factor contributing to the development and symptom severity of psychosis. Despite the fact that various cognitive biases are contributing to psychosis, they are rarely investigated together. In the current systematic review, we aimed at investigating specific and shared functional neural correlates of two important cognitive biases: aberrant salience and source monitoring. We conducted a systematic search of fMRI studies of said cognitive biases. Eight studies on aberrant salience and eleven studies on source monitoring were included in the review. We critically discussed behavioural and neuroimaging findings concerning cognitive biases. Various brain regions are associated with aberrant salience and source monitoring in individuals with schizophrenia and the risk of psychosis. The ventral striatum and insula contribute to aberrant salience. The medial prefrontal cortex, superior and middle temporal gyrus contribute to source monitoring. The anterior cingulate cortex and hippocampus contribute to both cognitive biases, constituting a neural overlap. Our review indicates that aberrant salience and source monitoring may share neural mechanisms, suggesting their joint role in producing disrupted external attributions of perceptual and cognitive experiences, thus elucidating their role in positive symptoms of psychosis. Account bridging mechanisms of these two biases is discussed. Further studies are warranted.

Indexed as

aberrant saliencecognitive biasesfMRIneuralpsychosisself-disturbancesource monitoring

Identifiers

PMID34575237
PMCPMC8468329
OpenAlexW3199947281

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.