ArticleJournal of clinical medicine2021
Endometriosis Is Associated with an Increased Risk of Coronary Artery Disease in Asian Women.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Endometriosis and cardiovascular disease risk: a meta-analysis of cohort studies.Annals of medicine · 2026Pooled it
- Risk of cardiovascular disease and mortality among women with endometriosis: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2026Pooled it
- Pooled it
- Endometriosis and risk of cardiovascular disease: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Endometriosis and aspirin: a systematic review.Frontiers in endocrinology · 2024Pooled it
- Associations between atherogenic index of plasma and endometriosis: The National Health and Nutrition Examination Survey 1999 to 2006.Medicine · 2026Article
- TCF21 promotes epithelial-to-mesenchymal transition and cytoskeleton reorganization in uterine development and endometriosis.Nature communications · 2026Article
- Aspirin does not modify cardiovascular event risk in endometriosis in the California Teachers Study.European heart journal open · 2025Article
- Laparoscopically confirmed endometriosis and the risk of incident NAFLD: a prospective cohort study.Reproductive biology and endocrinology : RB&E · 2025Article
- Association between Ovarian Endometriomas and Stage of Endometriosis.Journal of clinical medicine · 2024Article
- Ischemic stroke with concomitant clear cell carcinoma of the ovary: A case report and review of literature.World journal of clinical cases · 2024Article
- The Prevalence of Endometriosis in Patients with Unexplained Infertility.Journal of clinical medicine · 2024Article
- Causal Association Between Endometriosis and Coronary Heart Disease: Evidence from the National Health and Nutrition Examination Survey and Mendelian Randomization Analysis.International journal of women's health · 2024Article
- Prevalence of sleep disturbances in endometriosis patients: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Review
- Endometriosis promotes atherosclerosis in a murine model.American journal of obstetrics and gynecology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a common systemic chronic inflammatory disease. Inflammation is the key mechanism responsible for the development of endothelial dysfunction and atherosclerosis. We aimed to investigate the risk of coronary artery disease (CAD) among Asian women with endometriosis. This retrospective population-based cohort study included patients with endometriosis diagnosed from 2000 to 2012 and registered in the Longitudinal Health Insurance Database, Taiwan. The comparison cohort (those without endometriosis) were selected (1:4) by matching the age frequency and the index year. We followed up the patients until the diagnosis of CAD (ICD-9-CM codes: 410-414, A270, and A279), withdrawal from the National Health Insurance system, death, or the end of the study. We used a multivariable-adjusted Cox proportional hazard model for evaluating the risk of CAD. We included 19,454 patients with endometriosis and 77,816 women as a comparison group. The mean age of the women at the diagnosis of endometriosis was 37.4 years. A total of 3245 women developed CAD in both groups during a median follow-up of 7 years. The incidence of CAD was higher in women with endometriosis than in those without (5.96 vs. 4.38 per 10,000 person-years; adjusted hazard ratio [95% confidence interval], 1.34 [1.22-1.47]). In conclusion, Asian women with endometriosis had a significantly higher risk of CAD. Further large-scale studies are needed to elucidate the cause-effect relationship between endometriosis and CAD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.