Evidence map›Paper›PMID 34575767›Full record

ReviewJournal of fungi (Basel, Switzerland)2021

The Role of the Cell Integrity Pathway in Septum Assembly in Yeast.

Cesar Roncero, Rubén Celador, Noelia Sánchez, Patricia García, Yolanda Sánchez

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Application and Mechanism of Action of Carvacrol AgainstJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Special Issue "The Fungal Cell Wall Integrity Pathway".Journal of fungi (Basel, Switzerland) · 2023
    Article
  7. Analysis of the Localization ofInternational journal of molecular sciences · 2023
    Article
  8. Review
  9. Journal of fungi (Basel, Switzerland) · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cesar RonceroDepartamento de Microbiología y Genética, Instituto de Biología Funcional y Genómica, CSIC/Universidad de Salamanca, C/Zacarías González, s/n, 37007 Salamanca, Spain.
Rubén CeladorDepartamento de Microbiología y Genética, Instituto de Biología Funcional y Genómica, CSIC/Universidad de Salamanca, C/Zacarías González, s/n, 37007 Salamanca, Spain.ORCID 0000-0001-6398-0147
Noelia SánchezDepartamento de Microbiología y Genética, Instituto de Biología Funcional y Genómica, CSIC/Universidad de Salamanca, C/Zacarías González, s/n, 37007 Salamanca, Spain.
Patricia GarcíaDepartamento de Microbiología y Genética, Instituto de Biología Funcional y Genómica, CSIC/Universidad de Salamanca, C/Zacarías González, s/n, 37007 Salamanca, Spain.ORCID 0000-0001-7513-1847
Yolanda SánchezDepartamento de Microbiología y Genética, Instituto de Biología Funcional y Genómica, CSIC/Universidad de Salamanca, C/Zacarías González, s/n, 37007 Salamanca, Spain.
Universidad de Salamanca · ES

Funding

Junta de Castilla y Leon CLU-2017-03Junta de Castilla y Leon SA116G19Ministerio de Ciencia, Innovación y Universidades BFU2017-84508-P
6 · The paper itself

Abstract

Cytokinesis divides a mother cell into two daughter cells at the end of each cell cycle and proceeds via the assembly and constriction of a contractile actomyosin ring (CAR). Ring constriction promotes division furrow ingression, after sister chromatids are segregated to opposing sides of the cleavage plane. Cytokinesis contributes to genome integrity because the cells that fail to complete cytokinesis often reduplicate their chromosomes. While in animal cells, the last steps of cytokinesis involve extracellular matrix remodelling and mid-body abscission, in yeast, CAR constriction is coupled to the synthesis of a polysaccharide septum. To preserve cell integrity during cytokinesis, fungal cells remodel their cell wall through signalling pathways that connect receptors to downstream effectors, initiating a cascade of biological signals. One of the best-studied signalling pathways is the cell wall integrity pathway (CWI) of the budding yeast

Indexed as

actomyosin ringcell integritycytokinesisseptumyeast

Identifiers

PMID34575767
PMCPMC8471060
OpenAlexW3198014196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.