Evidence map›Paper›PMID 34575785›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

The Long-Acting Echinocandin, Rezafungin, Prevents Pneumocystis Pneumonia and Eliminates Pneumocystis from the Lungs in Prophylaxis and Murine Treatment Models.

Melanie T Cushion, Alan Ashbaugh

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Rezafungin as Primary Prophylaxis ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. JHLT open · 2025
    Article
  5. Article
  6. Review
  7. Clinical microbiology reviews · 2024
    Review
  8. New Approaches to Manage Infections in Transplant Recipients: Report From the 2023 GTI (Infection and Transplantation Group) Annual Meeting.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Melanie T CushionDepartment of Internal Medicine, Division of Infectious Diseases, College of Medicine, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0001-6621-2784
Alan AshbaughDepartment of Internal Medicine, Division of Infectious Diseases, College of Medicine, University of Cincinnati, Cincinnati, OH 45221, USA.
Cincinnati VA Medical Center · US

Funding

The role of sex in the life cycle and transmission of PneumocystisR01HL146266 · NHLBI · UNIVERSITY OF CINCINNATI · PI CUSHION, MELANIE T · 2019 to 2022
$1.9M
BLRD VA I01 BX004441BLRD VA IK6 BX005232Cidara Therapeutics noneNHLBI NIH HHS R01 HL146266
6 · The paper itself

Abstract

Rezafungin is a novel echinocandin in Phase 3 development for prevention of invasive fungal disease caused by

Indexed as

echinocandinobligate sexual reproductionPCPPneumocystis jirovecii pneumonia (PJP) Pneumocystisrezafungin

Identifiers

PMID34575785
PMCPMC8468546
OpenAlexW3198916239

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.