Evidence map›Paper›PMID 34575826›Full record

ArticleInternational journal of molecular sciences2021

Alteration of the Early Development Environment by Maternal Diet and the Occurrence of Autistic-like Phenotypes in Rat Offspring.

Kinga Gawlińska, Dawid Gawliński, Ewelina Kowal-Wiśniewska, Małgorzata Jarmuż-Szymczak, Małgorzata Filip

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kinga GawlińskaDepartment of Drug Addiction Pharmacology, Maj Institute of Pharmacology Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.ORCID 0000-0001-7015-154X
Dawid GawlińskiDepartment of Drug Addiction Pharmacology, Maj Institute of Pharmacology Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.ORCID 0000-0002-9376-0564
Ewelina Kowal-WiśniewskaInstitute of Human Genetics, Polish Academy of Sciences, Strzeszyńska 32, 60-479 Poznań, Poland.ORCID 0000-0002-6680-8825
Małgorzata Jarmuż-SzymczakInstitute of Human Genetics, Polish Academy of Sciences, Strzeszyńska 32, 60-479 Poznań, Poland.ORCID 0000-0003-0437-5806
Małgorzata FilipDepartment of Drug Addiction Pharmacology, Maj Institute of Pharmacology Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.ORCID 0000-0002-4321-7942
Maj Institute of Pharmacology · PLInstitute of Human Genetics · PL

Funding

Narodowe Centrum Nauki 2018/29/N/NZ7/02703Narodowe Centrum Nauki 2020/36/T/NZ7/00540
6 · The paper itself

Abstract

Epidemiological and preclinical studies suggest that maternal obesity increases the risk of autism spectrum disorder (ASD) in offspring. Here, we assessed the effects of exposure to modified maternal diets limited to pregnancy and lactation on brain development and behavior in rat offspring of both sexes. Among the studied diets, a maternal high-fat diet (HFD) disturbed the expression of ASD-related genes (

Indexed as

Prenatal Exposure Delayed EffectsAnimal FeedAnimalsAutistic DisorderDiet, High-FatDisease Models, AnimalDisease SusceptibilityDNA MethylationEnvironmental ExposureEpigenesis, GeneticFemaleGestational AgeLactationMaleMaternal ExposurePhenotypeASDautism spectrum disorderepigeneticsHFDhigh-fat dietmaternal dietoffspring behaviorsprefrontal cortexpregnancy and lactation

Identifiers

PMID34575826
PMCPMC8472469
OpenAlexW3198326262

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.