Evidence map›Paper›PMID 34576114›Full record

ReviewInternational journal of molecular sciences2021

Molecular Landscapes of Gastric Pre-Neoplastic and Pre-Invasive Lesions.

Gianluca Businello, Valentina Angerilli, Paola Parente, Stefano Realdon, Edoardo Savarino, Fabio Farinati, Federica Grillo, Alessandro Vanoli, Francesca Galuppini, Silvia Paccagnella and 4 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Targetable pathways for drug repurposing in gastric cancer.World journal of gastroenterology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Matrix Metalloproteinases inInternational journal of molecular sciences · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gianluca BusinelloSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35121 Padua, Italy.
Valentina AngerilliSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35121 Padua, Italy.
Paola ParentePathology Unit, Fondazione IRCCS Ospedale Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy.ORCID 0000-0003-0591-6723
Stefano RealdonVeneto Institute of Oncology (IOV-IRCCS), 35128 Padua, Italy.
Edoardo SavarinoDivision of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-3187-2894
Fabio FarinatiDivision of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, 35121 Padua, Italy.
Federica GrilloAnatomic Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DICS), University of Genova, 16132 Genova, Italy.ORCID 0000-0001-6477-3182
Alessandro VanoliAnatomic Pathology Unit, Department of Molecular Medicine, University of Pavia and Fondazione IRCCS San Matteo Hospital, 27100 Pavia, Italy.ORCID 0000-0002-2976-7032
Francesca GaluppiniSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35121 Padua, Italy.ORCID 0000-0002-3245-2322
Silvia PaccagnellaSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35121 Padua, Italy.
Gianmaria PennelliSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35121 Padua, Italy.
Luca MastracciAnatomic Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DICS), University of Genova, 16132 Genova, Italy.
Luca SaragoniUO Anatomia Patologica, Ospedale G.B. Morgagni-L. Pierantoni, 47121 Forlì, Italy.ORCID 0000-0002-2137-9596
Matteo FassanSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, 35121 Padua, Italy.ORCID 0000-0001-6515-5482

Funding

Italian Health Ministry and Veneto Region NET-2016-02363853
6 · The paper itself

Abstract

Gastric carcinoma (GC) represents one of the most common and most lethal malignancies worldwide. The histopathological characterization of GC precursor lesions has provided great knowledge about gastric carcinogenesis, with the consequent introduction of effective strategies of primary and secondary prevention. In recent years, a large amount of data about the molecular events in GC development is emerging, flanking the histomorphological descriptions. In this review, we describe the landscape of molecular alterations in gastric pre-invasive lesions with a glance at their potential use in the diagnostic and therapeutic decision-making process.

Indexed as

HumansMolecular Targeted TherapyNeoplasm InvasivenessPrecancerous ConditionsRisk FactorsStomach Neoplasmsbiomarkersgastric carcinogenesisgastric carcinomapathologypre-neoplastic lesions

Identifiers

PMID34576114
PMCPMC8468646

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.