Evidence map›Paper›PMID 34576167›Full record

ArticleInternational journal of molecular sciences2021

Primary Human Colon Epithelial Cells (pHCoEpiCs) Do Express the Shiga Toxin (Stx) Receptor Glycosphingolipids Gb3Cer and Gb4Cer and Are Largely Refractory but Not Resistant towards Stx.

Johanna Detzner, Charlotte Püttmann, Gottfried Pohlentz, Hans-Ulrich Humpf, Alexander Mellmann, Helge Karch, Johannes Müthing

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. EnterohemorrhagicInternational journal of molecular sciences · 2022
    Review
  3. Ingenious Action ofMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Johanna DetznerInstitute for Hygiene, University of Münster, 48149 Münster, Germany.
Charlotte PüttmannInstitute for Hygiene, University of Münster, 48149 Münster, Germany.
Gottfried PohlentzInstitute for Hygiene, University of Münster, 48149 Münster, Germany.
Hans-Ulrich HumpfInstitute for Food Chemistry, University of Münster, 48149 Münster, Germany.
Alexander MellmannInstitute for Hygiene, University of Münster, 48149 Münster, Germany.ORCID 0000-0002-0649-5185
Helge KarchInstitute for Hygiene, University of Münster, 48149 Münster, Germany.
Johannes MüthingInstitute for Hygiene, University of Münster, 48149 Münster, Germany.ORCID 0000-0001-9958-3514
University of Münster · DE

Funding

German Center for Infection Research TTU 06.909German Federal Ministry of Education and Research (BMBF) TTU 06.909German Research Foundation (DFG) MU845/7-1SFB 1009 194468054
6 · The paper itself

Abstract

Shiga toxin (Stx) is released by enterohemorrhagic

Indexed as

Cell LineCells, CulturedChromatography, Thin LayerColonEpithelial CellsGlobosidesGlycosphingolipidsHumansMass SpectrometryShiga ToxinSyntaxin 1TrihexosylceramidesGlobosidesglobotetraosylceramideglobotriaosylceramideGlycosphingolipidsShiga ToxinSTX1A protein, humanSyntaxin 1Trihexosylceramidescolon epithelial cellsGb3CerGb4CerglycosphingolipidsStx1aStx2aStx2e

Identifiers

PMID34576167
PMCPMC8472147
OpenAlexW3201468934

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.