Evidence map›Paper›PMID 34576341›Full record

ArticleInternational journal of molecular sciences2021

Blockade of Serotonin 5-HT

Emilie Doucet, Katarzyna Grychowska, Pawel Zajdel, Joël Bockaert, Philippe Marin, Carine Bécamel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Low-Basicity 5-HTInternational journal of molecular sciences · 2024
    Article
  4. Impact of 5-HTCells · 2023
    Review
  5. Article
  6. Role of nerves in neurofibromatosis type 1-related nervous system tumors.Cellular oncology (Dordrecht, Netherlands) · 2022
    Review
  7. Pathophysiology of the Serotonin System in the Nervous System and Beyond.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emilie DoucetInstitute of Functional Genomics, University of Montpellier, CNRS, Inserm, 34094 Montpellier, France.
Katarzyna GrychowskaDepartment of Organic Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland.
Pawel ZajdelDepartment of Organic Chemistry, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland.ORCID 0000-0002-6192-8721
Joël BockaertInstitute of Functional Genomics, University of Montpellier, CNRS, Inserm, 34094 Montpellier, France.
Philippe MarinInstitute of Functional Genomics, University of Montpellier, CNRS, Inserm, 34094 Montpellier, France.ORCID 0000-0002-5977-7274
Carine BécamelInstitute of Functional Genomics, University of Montpellier, CNRS, Inserm, 34094 Montpellier, France.ORCID 0000-0001-7385-681X

Funding

Centre National de la Recherche Scientifique DotationFondation pour la Recherche Médicale DPA20140629800French Association Kokcinelo financial supportInstitut National de la Santé et de la Recherche Médicale DotationLaboratoire d'Excellence EpiGenMed Postdoctoral FellowshipNeurofibromatosis Northeast Post-doctoral fellowshipUniversité de Montpellier Dotation
6 · The paper itself

Abstract

Neurofibromatosis type 1 (NF1) is a common inherited disorder caused by mutations of the

Indexed as

AnimalsHumansNeurofibromatosis 1Receptors, SerotoninSerotoninThiophenes5-((5-methyl-3-thienyl)oxy)-2(1H)-pyrimidinoneReceptors, SerotoninSerotoninserotonin 6 receptorThiophenes5-HT6 receptorcognitionconstitutive activityinverse agonistmTORneurofibromatosis type 1neutral antagonistrapamycin

Identifiers

PMID34576341
PMCPMC8467191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.