Evidence map›Paper›PMID 34577146›Full record

ArticleMolecules (Basel, Switzerland)2021

Interaction of (+)-Strebloside and Its Derivatives with Na

Yulin Ren, Sijin Wu, Sijie Chen, Joanna E Burdette, Xiaolin Cheng, A Douglas Kinghorn

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Digoxin and its NaBioorganic & medicinal chemistry · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yulin RenDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-3667-1466
Sijin WuDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Sijie ChenDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Joanna E BurdetteDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA.
Xiaolin ChengDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
A Douglas KinghornDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-6647-8707
The Ohio State University · USUniversity of Illinois Chicago · US

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI JIMMY ORJALA · 2007 to 2026
$27.2M
NCI NIH HHS P01 CA125066NIH HHS P01 CA125066
6 · The paper itself

Abstract

Docking profiles for (+)-strebloside, a cytotoxic cardiac glycoside identified from

Indexed as

Cardiac GlycosidesMolecular Docking SimulationSodium-Potassium-Exchanging ATPaseDigoxinHumansKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Phosphatidylinositol 3-KinasesProtein BindingStrophanthinsCardiac GlycosidesDigoxinKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Phosphatidylinositol 3-KinasesSodium-Potassium-Exchanging ATPaseStrophanthinscytotoxicitydocking profilesmolecular targetsNa+/K+-ATPase(+)-strebloside

Identifiers

PMID34577146
PMCPMC8467840
OpenAlexW3201409358

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.