ArticlePathogens (Basel, Switzerland)2021
The Antimicrobial and Antibiofilm In Vitro Activity of Liquid and Vapour Phases of Selected Essential Oils against
Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The antibacterial effectiveness of lavender essential oil against methicillin-resistantFrontiers in pharmacology · 2023Pooled it
- Exploitation of Nanoparticle-Essential Oil Combinations to Enhance the Efficacy of Antimicrobial Agents AgainstPharmaceutics · 2026Article
- Antibiofilm Activity of Three Essential Oils Against ESBL-ProducingAntibiotics (Basel, Switzerland) · 2026Article
- Can essential oils effectively control skin bacteria? Unveiling their powerful antimicrobial effects.Microbiology spectrum · 2026Article
- Sustainable thymol-based formulations with amoxicillin andFrontiers in chemistry · 2026Article
- Essential Oils for Biofilm Control: Mechanisms, Synergies, and Translational Challenges in the Era of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Evaluating the Antimicrobial and Antibiofilm Efficacy of Lavender Essential Oil and Linalool on Dual Candida albicans Biofilms With Staphylococcus aureus and Staphylococcus epidermidis From Canine External Otitis.Veterinary medicine and science · 2025Article
- Inhibition of Biofilm Production and Determination of In Vitro Time-KillPathogens (Basel, Switzerland) · 2025Article
- Establishing essential oil stewardship through the case of rosemary and thyme oils againstFrontiers in microbiology · 2025Article
- Essential oils and their blends: mechanism of antibacterial activity and antibiofilm potential on food-grade maize starch packaging films.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Potential Anti-Infectious Activity of Essential Oil Chemotypes ofPlants (Basel, Switzerland) · 2024Article
- The chronic wound milieu changes essential oils' antibiofilm activity-an in vitro and larval model study.Scientific reports · 2024Article
- Antibacterial and Antibiofilm Effects of Different Samples of Five Commercially Available Essential Oils.Antibiotics (Basel, Switzerland) · 2023Article
- Tea Tree Oil: Properties and the Therapeutic Approach to Acne-A Review.Antioxidants (Basel, Switzerland) · 2023Review
- Effects ofMolecules (Basel, Switzerland) · 2023Article
- Agar Plate Methods for Assessing the Antibacterial Activity of Thyme and Oregano Essential Oils againstAntibiotics (Basel, Switzerland) · 2022Article
- Chemical Composition and Antibacterial Activity of Liquid and Volatile Phase of Essential Oils against Planktonic and Biofilm-Forming Cells ofMolecules (Basel, Switzerland) · 2022Article
- Phytochemicals Profiling, Antimicrobial Activity and Mechanism of Action of Essential Oil Extracted from Ginger (Plants (Basel, Switzerland) · 2022Article
- Chemical and Biological Characterization ofPlants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The high resistance of staphylococcal biofilm against antibiotics and developing resistance against antiseptics induces a search for novel antimicrobial compounds. Due to acknowledged and/or alleged antimicrobial activity of EOs, their application seems to be a promising direction to follow. Nevertheless, the high complexity of EOs composition and differences in laboratory protocols of the antimicrobial activity assessment hinders the exact estimation of EOs effectiveness. To overcome these disadvantages, in the present work we analysed the effectiveness of volatile and liquid forms of seven EOs (derived from thyme, tea tree, basil, rosemary, eucalyptus, lavender, and menthol mint) against 16 staphylococcal biofilm-forming strains using cohesive set of in vitro techniques, including gas chromatography-mass spectrometry, inverted Petri dish, modified disk-diffusion assay, microdilution techniques, antibiofilm dressing activity measurement, AntiBioVol protocol, fluorescence/confocal microscopy, and dynamic light scattering. Depending on the requirements of the technique, EOs were applied in emulsified or non-emulsified form. The obtained results revealed that application of different in vitro techniques allows us to get a comprehensive set of data and to gain insight into the analysed phenomena. In the course of our investigation, liquid and volatile fractions of thyme EO displayed the highest antibiofilm activity. Liquid fractions of rosemary oil were the second most active against
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.