Evidence map›Paper›PMID 34578377›Full record

ArticleViruses2021

Histotype-Dependent Oligodendroglial PrP Pathology in Sporadic CJD: A Frequent Feature of the M2C "Strain".

Ellen Gelpi, Sigrid Klotz, Nuria Vidal-Robau, Gerda Ricken, Günther Regelsberger, Thomas Ströbel, Ognian Kalev, Marlene Leoni, Herbert Budka, Gabor G Kovacs

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Ellen GelpiDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-2948-4187
Sigrid KlotzDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-3096-2852
Nuria Vidal-RobauDepartment of Neurology, Bellvitge University Hospital, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
Gerda RickenDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-0388-7965
Günther RegelsbergerDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.
Thomas StröbelDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.
Ognian KalevDepartment of Neuropathology/Pathology, Kepler Universitäts Klinikum, 4020 Linz, Austria.
Marlene LeoniDepartment of Neuropathology/Pathology, Medical University Graz, 8036 Graz, Austria.
Herbert BudkaDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-1933-1577
Gabor G KovacsTanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, ON M5T 0S8, Canada.ORCID 0000-0003-3841-5511
Medical University of Vienna · ATBellvitge University Hospital · ESKepler Universitätsklinikum · ATMedical University of Graz · ATUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In sporadic Creutzfeldt-Jakob disease, molecular subtypes are neuropathologically well identified by the lesioning profile and the immunohistochemical PrP

Indexed as

PhenotypeAgedAged, 80 and overBrainCreutzfeldt-Jakob SyndromeEncephalopathy, Bovine SpongiformFemaleGenotypeHumansMaleMiddle AgedOligodendrogliaPrionsPrPSc ProteinsPrionsPrPSc ProteinsCJDCreutzfeldt-Jakob diseasegliahistotypeoligodendrocytesprionPrP

Identifiers

PMID34578377
PMCPMC8473396
OpenAlexW3198633689

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.