Evidence map›Paper›PMID 34579064›Full record

Trial reportNutrients2021

Krill Protein Hydrolysate Provides High Absorption Rate for All Essential Amino Acids-A Randomized Control Cross-Over Trial.

Rebekka Thøgersen, Hanne Christine Bertram, Mathias T Vangsoe, Mette Hansen

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rebekka ThøgersenDepartment of Food Science, Aarhus University, Agro Food Park 48, 8200 Aarhus N, Denmark.
Hanne Christine BertramDepartment of Food Science, Aarhus University, Agro Food Park 48, 8200 Aarhus N, Denmark.ORCID 0000-0002-1882-5321
Mathias T VangsoeAker Biomarine Antarctic AS, Oksenøyveien 10, NO-1327 Lysaker, Norway.ORCID 0000-0003-2597-8403
Mette HansenDepartment for Public Health, Aarhus University, Dalgas Av. 4, 8000 Aarhus C, Denmark.ORCID 0000-0002-9383-8202
Aarhus University · DK

Funding

Aker Biomarine Antarctic AS 32805
6 · The paper itself

Abstract

backgroundadequate protein intake is essential to humans and, since the global demand for protein-containing foods is increasing, identifying new high-quality protein sources is needed. In this study, we investigated the acute postprandial bioavailability of amino acids (AAs) from a krill protein hydrolysate compared to a soy and a whey protein isolate.

methodsthe study was a randomized, placebo-controlled crossover trial including ten healthy young males. On four non-consecutive days, volunteers consumed water or one of three protein-matched supplements: whey protein isolate, soy protein isolate or krill protein hydrolysate. Blood samples were collected prior to and until 180 min after consumption. Serum postprandial AA concentrations were determined using

resultswhey and krill resulted in significantly higher AA concentrations compared to soy between 20-60 min and 20-40 min after consumption, respectively. Area under the curve (AUC) analyses revealed that whey resulted in the highest postprandial serum concentrations of essential AAs (EAAs) and branched chain AAs (BCAAs), followed by krill and soy, respectively.

conclusionskrill protein hydrolysate increases postprandial serum EAA and BCAA concentrations in a superior manner to soy protein isolate and thus might represent a promising future protein source in human nutrition.

Indexed as

Dietary SupplementsNutritive ValueAdultAmino Acids, Branched-ChainAmino Acids, EssentialAnimalsArea Under CurveBiological AvailabilityCross-Over StudiesDigestionEuphausiaceaHumansHungerMagnetic Resonance SpectroscopyMalePostprandial PeriodAmino Acids, Branched-ChainAmino Acids, EssentialProtein HydrolysatesSoybean ProteinsWhey Proteinsalternative proteinsamino acidhumankrill proteinmarine proteinNMR spectroscopypostprandial absorptionprotein accessibilityprotein hydrolysatesoywhey

Identifiers

PMID34579064
PMCPMC8465607
OpenAlexW3198946131

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.