Evidence map›Paper›PMID 34579077›Full record

Trial reportNutrients2021

A Pilot Randomized Controlled Trial of a Partial Meal Replacement Preconception Weight Loss Program for Women with Overweight and Obesity.

Roslyn Muirhead, Nathalie Kizirian, Ravin Lal, Kirsten Black, Ann Prys-Davies, Natasha Nassar, Louise Baur, Amanda Sainsbury, Arianne Sweeting, Tania Markovic and 6 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Weight management in women of reproductive age.Obesity and endocrinology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Roslyn MuirheadCharles Perkins Centre, School of Life and Environmental Biosciences, University of Sydney, Sydney, NSW 2006, Australia.
Nathalie KizirianCharles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia.
Ravin LalCharles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia.
Kirsten BlackSpeciality of Obstetrics, Gynaecology and Neonatology, Central Clinical School, Faculty of Medicine and Health, Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia.
Ann Prys-DaviesDepartment of Women and Babies, Royal Prince Alfred Hospital, Sydney Local Health District, Sydney, NSW 2050, Australia.
Natasha NassarCharles Perkins Centre, Childrens Hospital Westmead Clinical School, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-3720-9655
Louise BaurCharles Perkins Centre, Childrens Hospital Westmead Clinical School, University of Sydney, Sydney, NSW 2006, Australia.
Amanda SainsburySchool of Human Sciences, Faculty of Science, University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0001-9176-1574
Arianne SweetingSydney Medical School, The University of Sydney, NSW 2006, Australia.ORCID 0000-0001-6843-6247
Tania MarkovicSydney Medical School, The University of Sydney, NSW 2006, Australia.ORCID 0000-0003-2521-0357
Michael SkiltonSydney Medical School, The University of Sydney, NSW 2006, Australia.ORCID 0000-0003-2793-2388
Jon HyettSpeciality of Obstetrics, Gynaecology and Neonatology, Central Clinical School, Faculty of Medicine and Health, Royal Prince Alfred Hospital Newborn Care, Sydney Local Health District, Sydney, NSW 2050, Australia.
Bradley de VriesSpeciality of Obstetrics, Gynaecology and Neonatology, Central Clinical School, Faculty of Medicine and Health, Royal Prince Alfred Hospital Newborn Care, Sydney Local Health District, Sydney, NSW 2050, Australia.
William Tarnow-MordiClinical Trial Centre, Department of Neonatology, University of Sydney, Westmead Hospital, Sydney, NSW 2006, Australia.
Jennie Brand-MillerCharles Perkins Centre, School of Life and Environmental Biosciences, University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-6797-8754
Adrienne GordonSpeciality of Obstetrics, Gynaecology and Neonatology, Central Clinical School, Faculty of Medicine and Health, Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia.

Funding

National Health and Medical Research Council GNT1089898University of Sydney DVC Research/Bridging Support Grant. N/A
6 · The paper itself

Abstract

About half of Australian women have a body mass index in the overweight or obese range at the start of pregnancy, with serious consequences including preterm birth, gestational hypertension and diabetes, caesarean section, stillbirth, and childhood obesity. Trials to limit weight gain during pregnancy have had limited success and reducing weight before pregnancy has greater potential to improve outcomes. The PreBabe Pilot study was a randomised controlled pilot trial to assess the feasibility, acceptability and potential weight loss achieved using a commercial online partial meal replacement program, (MR) vs. telephone-based conventional dietary advice, (DA) for pre-conception weight-loss over a 10-week period. Women 18-40 years of age with a BMI ≥ 25 kg/m

Indexed as

CounselingMealsTelephoneWeight Reduction ProgramsAdultFemaleHumansOverweightPilot Projectsclinical trialmeal replacementobesitypreconceptionweight loss

Identifiers

PMID34579077
PMCPMC8469733

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.